Brain-derived neurotrophic factor and diabetes

O Rozanska, A Uruska… - International journal of …, 2020 - mdpi.com
Diabetes and its chronic complications still represent a great clinical problem, despite
improvements made in the diagnosis and treatment of the disease. People with diabetes …

Nutraceuticals for the treatment of diabetic retinopathy

MG Rossino, G Casini - Nutrients, 2019 - mdpi.com
Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus and
is characterized by degeneration of retinal neurons and neoangiogenesis, causing a severe …

The innate immune system in diabetic retinopathy

WW Pan, F Lin, PE Fort - Progress in retinal and eye research, 2021 - Elsevier
The prevalence of diabetes has been rising steadily in the past half-century, along with the
burden of its associated complications, including diabetic retinopathy (DR). DR is currently …

Recent advances in the treatment and delivery system of diabetic retinopathy

Z Wang, N Zhang, P Lin, Y **ng, N Yang - Frontiers in Endocrinology, 2024 - frontiersin.org
Diabetic retinopathy (DR) is a highly tissue-specific neurovascular complication of type 1
and type 2 diabetes mellitus and is among the leading causes of blindness worldwide …

Neurodegeneration in the pathogenesis of diabetic retinopathy: molecular mechanisms and therapeutic implications

M S. Stem, T W. Gardner - Current medicinal chemistry, 2013 - benthamdirect.com
Diabetic retinopathy (DR), commonly classified as a microvascular complication of diabetes,
is now recognized as a neurovascular complication or sensory neuropathy resulting from …

Brain-derived neurotrophic factor in diabetes mellitus: A systematic review and meta-analysis

F Moosaie, S Mohammadi, A Saghazadeh… - PLoS …, 2023 - journals.plos.org
Background Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor expressed in
several tissues, including the brain, gut, and pancreas. Activation of the BDNF/TrkB/CREB …

Flavonoid naringenin attenuates oxidative stress, apoptosis and improves neurotrophic effects in the diabetic rat retina

DI Al-Dosari, MM Ahmed, SS Al-Rejaie, AS Alhomida… - Nutrients, 2017 - mdpi.com
Diabetic retinopathy (DR) is one of the leading causes of decreased vision and blindness
worldwide. Diabetes-induced oxidative stress is believed to be the key factor that initiates …

Is type 2 diabetes mellitus associated with alterations in hearing? A systematic review and meta‐analysis

OV Akinpelu, M Mujica‐Mota, SJ Daniel - The Laryngoscope, 2014 - Wiley Online Library
Objectives/Hypothesis The aim of this study was to systematically and quantitatively review
the available evidence on the effects of type 2 diabetes mellitus on hearing function. Data …

[HTML][HTML] Aging and diabetic retinopathy: Inherently intertwined pathophysiological processes

Q Li, M Wang, X Li, Y Shao - Experimental Gerontology, 2023 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness worldwide and a costly
complication of diabetes mellitus (DM). DR severity is associated with DM duration; thus, DR …

Roles of miRNAs and long noncoding RNAs in the progression of diabetic retinopathy

Q Gong, G Su - Bioscience Reports, 2017 - portlandpress.com
Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults across the
world. The pathogenesis of DR is multifactorial and the molecular mechanisms are still not …