[HTML][HTML] RIG-I-like receptors: their regulation and roles in RNA sensing
J Rehwinkel, MU Gack - Nature Reviews Immunology, 2020 - nature.com
Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are key sensors of virus
infection, mediating the transcriptional induction of type I interferons and other genes that …
infection, mediating the transcriptional induction of type I interferons and other genes that …
Immune signaling by RIG-I-like receptors
YM Loo, M Gale - Immunity, 2011 - cell.com
The RIG-I-like receptors (RLRs) RIG-I, MDA5, and LGP2 play a major role in pathogen
sensing of RNA virus infection to initiate and modulate antiviral immunity. The RLRs detect …
sensing of RNA virus infection to initiate and modulate antiviral immunity. The RLRs detect …
Getting the “kill” into “shock and kill”: strategies to eliminate latent HIV
Y Kim, JL Anderson, SR Lewin - Cell host & microbe, 2018 - cell.com
Despite the success of antiretroviral therapy (ART), there is currently no HIV cure and
treatment is life long. HIV persists during ART due to long-lived and proliferating latently …
treatment is life long. HIV persists during ART due to long-lived and proliferating latently …
[HTML][HTML] Virus inhibition of RIP3-dependent necrosis
Viral infection activates cytokine expression and triggers cell death, the modulation of which
is important for successful pathogenesis. Necroptosis is a form of programmed necrosis …
is important for successful pathogenesis. Necroptosis is a form of programmed necrosis …
Battle royale: innate recognition of poxviruses and viral immune evasion
Host pattern recognition receptors (PRRs) sense pathogen-associated molecular patterns
(PAMPs), which are molecular signatures shared by different pathogens. Recognition of …
(PAMPs), which are molecular signatures shared by different pathogens. Recognition of …
Poxviruses and the immune system: Implications for monkeypox virus
A Saghazadeh, N Rezaei - International Immunopharmacology, 2022 - Elsevier
Poxviruses (PXVs) are mostly known for the variola virus, being the cause of smallpox;
however, re-emerging PXVs have also shown a great capacity to develop outbreaks of pox …
however, re-emerging PXVs have also shown a great capacity to develop outbreaks of pox …
Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome
J Delaloye, T Roger, QG Steiner-Tardivel… - PLoS …, 2009 - journals.plos.org
Modified vaccinia virus Ankara (MVA) is an attenuated double-stranded DNA poxvirus
currently developed as a vaccine vector against HIV/AIDS. Profiling of the innate immune …
currently developed as a vaccine vector against HIV/AIDS. Profiling of the innate immune …
The crosstalk between viral RNA-and DNA-sensing mechanisms
C Cai, YD Tang, G Xu, C Zheng - Cellular and Molecular Life Sciences, 2021 - Springer
Viral infections pose a severe threat to humans by causing many infectious, even fatal,
diseases, such as the current pandemic disease (COVID-19) since 2019, and understanding …
diseases, such as the current pandemic disease (COVID-19) since 2019, and understanding …
Mitochondrial antiviral signaling protein plays a major role in induction of the fish innate immune response against RNA and DNA viruses
S Biacchesi, M LeBerre, A Lamoureux, Y Louise… - Journal of …, 2009 - Am Soc Microbiol
Viral infection triggers host innate immune responses through cellular sensor molecules
which activate multiple signaling cascades that induce the production of interferons (IFN) …
which activate multiple signaling cascades that induce the production of interferons (IFN) …
Myxomatosis in Australia and Europe: a model for emerging infectious diseases
PJ Kerr - Antiviral research, 2012 - Elsevier
Myxoma virus is a poxvirus naturally found in two American leporid (rabbit) species
(Sylvilagus brasiliensis and Sylvilagus bachmani) in which it causes an innocuous localised …
(Sylvilagus brasiliensis and Sylvilagus bachmani) in which it causes an innocuous localised …