[HTML][HTML] A survey of physical methods for studying nuclear mechanics and mechanobiology

CM Hobson, MR Falvo, R Superfine - APL bioengineering, 2021 - pubs.aip.org
It is increasingly appreciated that the cell nucleus is not only a home for DNA but also a
complex material that resists physical deformations and dynamically responds to external …

Chromatin and cancer: implications of disrupted chromatin organization in tumorigenesis and its diversification

P Sehgal, P Chaturvedi - Cancers, 2023 - mdpi.com
Simple Summary Human DNA is~ 2 m long, but is efficiently packaged in cell nucleus that is
a million times smaller. The concerted action of several enzymes enables this packaging …

X-rays induced alterations in mechanical and biochemical properties of isolated SH-SY5Y nuclei

L Andolfi, R Meschini, S Filippi, DE Bedolla… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Background The use of ionizing radiations in radiotherapy is an effective and very common
cancer treatment after surgery. Although ionizing-radiation DNA damages are extensively …

Changes in the properties of membrane tethers in response to hp1α depletion in mcf7 cells

S Pradhan, MAK Williams, TK Hale - Biochemical and Biophysical …, 2022 - Elsevier
Plasma membrane tension is known to regulate many cell functions, such as motility and
membrane trafficking. Membrane tether pulling is an effective method for measuring the …

[HTML][HTML] Biomechanical responses of encysted zoospores of the oomycete Achlya bisexualis to hyperosmotic stress are consistent with an ability to turgor regulate

N Lacalendola, A Tayagui, M Ting, J Malmstrom… - Fungal Genetics and …, 2022 - Elsevier
Zoospores are motile, asexual reproductive propagules that enable oomycete pathogens to
locate and infect new host tissue. While motile, they have no cell wall and maintain tonicity …

Biophysical Principles Underlying Assembly, Regulation, and Function of Intracellular Condensates

DSW Lee - 2021 - search.proquest.com
A major hallmark of biology is intricate organization and structural complexity. One crucial
example of this is the nucleus, which houses and protects the genome while coordinating …