Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

This review investigates the significant role polysaccharide particles play in functional drug
delivery. The importance of these systems is due to the wide variety of polysaccharides and …

Highlights•New modifications to hyaluronic acid (HA) enable both covalent crosslinking and
supramolecular assembly.•Composite HA hydrogels permit controlled drug delivery and …

Over the past decades, significant progress has been made in the field of hydrogels as
functional biomaterials. Biomedical application of hydrogels was initially hindered by the …

Hydrogels, microgels and nanogels have emerged as versatile and viable platforms for
sustained protein release, targeted drug delivery, and tissue engineering due to excellent …

Interrogating biological systems is often limited by access to biological probes. The
emergence of “click chemistry” has revolutionized bioconjugate chemistry by providing facile …

The conjugation of biomolecules can impart materials with the bioactivity necessary to
modulate specific cell behaviors. While the biological roles of particular polypeptide …

The desire and need to minimize traditional open surgeries is gearing up as it could reduce
the healthcare expenses and improve the recovery time for the patients. Minimal invasive …

Biological tissues, such as muscle, can increase their mechanical strength after swelling due
to the existence of many biological membrane barriers that can regulate the transmembrane …

This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …