Permeation enhancer strategies in transdermal drug delivery

H Marwah, T Garg, AK Goyal, G Rath - Drug delivery, 2016 - Taylor & Francis
Today,∼ 74% of drugs are taken orally and are not found to be as effective as desired. To
improve such characteristics, transdermal drug delivery was brought to existence. This …

Insights into the nature of eutectic and deep eutectic mixtures

MAR Martins, SP Pinho, JAP Coutinho - Journal of Solution Chemistry, 2019 - Springer
A stricter definition of a deep eutectic solvent (DES) is urgent, so that it may become a sound
basis for further developments in this field. This communication aims at contributing to …

Tunable hydrophobic eutectic solvents based on terpenes and monocarboxylic acids

MAR Martins, EA Crespo, PVA Pontes… - ACS Sustainable …, 2018 - ACS Publications
Recently, some works claim that hydrophobic deep eutectic solvents could be prepared
based on menthol and monocarboxylic acids. Despite of some promising potential …

Application of cellulose acetate for controlled release of thymol

S Milovanovic, D Markovic, K Aksentijevic… - Carbohydrate …, 2016 - Elsevier
Cellulose acetate (CA) was investigated as a carrier towards development of material with
controlled release of thymol as a natural substance with strong antibacterial properties using …

Strategies for meloxicam delivery to and across the skin: a review

J Chen, Y Gao - Drug Delivery, 2016 - Taylor & Francis
Although meloxicam (MX) is relatively safer than other NSAIDs, adverse effects relating to
the gastro-intestinal tract are still a problem when administrated MX at high doses and on …

Therapeutic deep eutectic system of capric acid and menthol: Characterization and pharmaceutical application

F Al-Akayleh, HHM Ali, MM Ghareeb… - Journal of Drug Delivery …, 2019 - Elsevier
The work outlined herein describes an evaluation of a new green solvent working as a drug
solubility enhancer made up of a eutectic system comprising mixtures of capric acid and …

Evaluation of deep eutectic solvents for the extraction of fucoxanthin from the alga Tisochrysis lutea–COSMO-RS screening and experimental validation

D Xu, J Chow, CC Weber, MA Packer… - Journal of …, 2022 - Elsevier
Fucoxanthin is a carotenoid in algae with purported beneficial health-related properties
including antioxidant, anti-photoaging, anti-metastasis, anti-hypertensive activity and more …

[HTML][HTML] Terpene-based eutectic mixtures for cutaneous delivery: Eutectic point vs. molar ratio-which matters more?

GS Czyrski, JJK Kirkensgaard, S Rønholt… - Journal of Molecular …, 2024 - Elsevier
Eutectic mixtures (EMs) of small molecules are increasingly used as a platform for dermal
and transdermal drug delivery. However, there is still limited knowledge about how their …

Preparation of solid lipid nanoparticles of cinnamaldehyde and determination of sustained release capacity

J Chen, S Li, Q Zheng, X Feng, W Tan, K Feng, Y Liu… - Nanomaterials, 2022 - mdpi.com
Natural plant essential oils cannot be applied on a large scale due to their high volatility,
easy deactivation, etc. This study provides a new method to prepare a long-lasting, slow …

Physicochemical characterization and simulation of the solid–liquid equilibrium phase diagram of terpene-based eutectic solvent systems

MM Abdallah, S Müller, A González de Castilla… - Molecules, 2021 - mdpi.com
The characterization of terpene-based eutectic solvent systems is performed to describe
their solid–liquid phase transitions. Physical properties are measured experimentally and …