Whole-genome duplication in teleost fishes and its evolutionary consequences
Whole-genome duplication (WGD) events have shaped the history of many evolutionary
lineages. One such duplication has been implicated in the evolution of teleost fishes, by far …
lineages. One such duplication has been implicated in the evolution of teleost fishes, by far …
Turning a hobby into a job: how duplicated genes find new functions
Gene duplication provides raw material for functional innovation. Recent advances have
shed light on two fundamental questions regarding gene duplication: which genes tend to …
shed light on two fundamental questions regarding gene duplication: which genes tend to …
The multiple fates of gene duplications: deletion, hypofunctionalization, subfunctionalization, neofunctionalization, dosage balance constraints, and neutral variation
Gene duplications have long been recognized as a contributor to the evolution of genes with
new functions. Multiple copies of genes can result from tandem duplication, from …
new functions. Multiple copies of genes can result from tandem duplication, from …
Gene balance hypothesis: connecting issues of dosage sensitivity across biological disciplines
We summarize, in this review, the evidence that genomic balance influences gene
expression, quantitative traits, dosage compensation, aneuploid syndromes, population …
expression, quantitative traits, dosage compensation, aneuploid syndromes, population …
The house spider genome reveals an ancient whole-genome duplication during arachnid evolution
Background The duplication of genes can occur through various mechanisms and is thought
to make a major contribution to the evolutionary diversification of organisms. There is …
to make a major contribution to the evolutionary diversification of organisms. There is …
Retention of duplicated genes in evolution
Gene duplication is a prevalent phenomenon across the tree of life. The processes that lead
to the retention of duplicated genes are not well understood. Functional genomics …
to the retention of duplicated genes are not well understood. Functional genomics …
Dosage, duplication, and diploidization: clarifying the interplay of multiple models for duplicate gene evolution over time
Highlights•Dosage balance is fluid and will change over time.•Duplicate genes are
preserved by interplay of multiple overlap** mechanisms.•Distinguishing duplicate gene …
preserved by interplay of multiple overlap** mechanisms.•Distinguishing duplicate gene …
Lineage-specific rediploidization is a mechanism to explain time-lags between genome duplication and evolutionary diversification
FM Robertson, MK Gundappa, F Grammes… - Genome biology, 2017 - Springer
Background The functional divergence of duplicate genes (ohnologues) retained from whole
genome duplication (WGD) is thought to promote evolutionary diversification. However …
genome duplication (WGD) is thought to promote evolutionary diversification. However …
Exploring whole-genome duplicate gene retention with complex genetic interaction analysis
INTRODUCTION Whole-genome duplication (WGD) events are pervasive in eukaryotes,
sha** the genomes of simple single-celled organisms, such as yeast, as well as those of …
sha** the genomes of simple single-celled organisms, such as yeast, as well as those of …
The gene balance hypothesis: implications for gene regulation, quantitative traits and evolution
The gene balance hypothesis states that the stoichiometry of members of multisubunit
complexes affects the function of the whole because of the kinetics and mode of assembly …
complexes affects the function of the whole because of the kinetics and mode of assembly …