Mechanism of regulating macrophages/osteoclasts in attenuating wear particle-induced aseptic osteolysis

Z Yin, G Gong, X Liu, J Yin - Frontiers in Immunology, 2023 - frontiersin.org
Joint replacement surgery is the most effective treatment for end-stage arthritis. Aseptic
loosening caused by periprosthetic osteolysis is a common complication after joint …

[HTML][HTML] Titanium alloy implants with lattice structures for mandibular reconstruction

KM Hijazi, SJ Dixon, JE Armstrong, AS Rizkalla - Materials, 2023 - mdpi.com
In recent years, the field of mandibular reconstruction has made great strides in terms of
hardware innovations and their clinical applications. There has been considerable interest …

Bimetallic metal–organic framework for mitigating aseptic osteolysis

H Pan, X Miao, J Deng, C Pan, X Cheng… - ACS Applied Materials …, 2023 - ACS Publications
The disability rate of joint diseases can be reduced by the use of artificial joints, but joint
loosening at a late state limits the lifespan and surgical efficacy of the joints. Wear particles …

[HTML][HTML] Laser beam powder bed fusion of novel biomedical titanium/niobium/tantalum alloys: Powder synthesis, microstructure evolution and mechanical properties

J Johannsen, C Lauhoff, M Stenzel, C Schnitter… - Materials & Design, 2023 - Elsevier
The synthesis of spherical titanium/niobium/tantalum (TNT) alloy powders, namely Ti-20Nb-
6Ta, Ti-27Nb-6Ta, Ti-35Nb-6Ta, and Ti-22Nb-19Ta (in wt-%) by electrode induction melting …

Mechanical and tribological assessment of composite AlCrN or aC: Ag-based thin films for implant application

L Patnaik, SR Maity, S Kumar - Ceramics International, 2021 - Elsevier
The present study focuses on the comparison of cathodic arc deposited AlCrN (ternary
coating) and Ag alloyed aC (amorphous carbon base coating) on chrome nitride (CrN) …

The mechanisms underlying the biological response to wear debris in periprosthetic inflammation

M Couto, DP Vasconcelos, DM Sousa, B Sousa… - Frontiers in …, 2020 - frontiersin.org
Joint replacement surgery is the gold-standard therapeutic approach to treat patients with
end-stage hip and knee arthritis, providing pain relief and joint function recovery. Despite the …

Glycolytic reprogramming underlies immune cell activation by polyethylene wear particles

CV Maduka, OM Habeeb, MM Kuhnert, M Hakun… - Biomaterials …, 2023 - Elsevier
Primary total joint arthroplasties (TJAs) are widely and successfully applied reconstructive
procedures to treat end-stage arthritis. Nearly 50% of TJAs are now performed in young …

Elevated oxidative phosphorylation is critical for immune cell activation by polyethylene wear particles

CV Maduka, MM Kuhnert, OM Habeeb, A Tundo… - Journal of Immunology …, 2023 - Elsevier
Chronic inflammation is a major concern after total joint replacements (TJRs), as it is
associated with bone loss, limited bone-implant integration (osseointegration), implant …

Evaluating and managing the painful total ankle replacement

JK Henry, C Rider, E Cody, SJ Ellis… - Foot & Ankle …, 2021 - journals.sagepub.com
The number of total ankle replacements (TARs) performed in the United States has
dramatically increased in the past 2 decades due to improvements in implant design and …

A universal biocompatible coating for enhanced lubrication and bacterial inhibition

D Suo, J Rao, H Wang, Z Zhang, PHM Leung… - Biomaterials …, 2022 - pubs.rsc.org
Antibacterial coatings that inhibit bacterial adhesion are essential for many implanted
medical devices. A variety of antibacterial strategies, such as repelling or killing bacteria …