Formulation and quality control of orally disintegrating tablets (ODTs): recent advances and perspectives

MP Ghourichay, SH Kiaie, A Nokhodchi… - BioMed Research …, 2021 - Wiley Online Library
Orally disintegrating tablets (ODTs) rapidly disintegrate or dissolve in the oral cavity without
using water. Demand for ODTs has increased, and the field has overgrown in the …

Cyclodextrin complexes: Perspective from drug delivery and formulation

S Jacob, AB Nair - Drug development research, 2018 - Wiley Online Library
Cyclodextrins (CDs) have been widely investigated as a unique pharmaceutical excipient for
past few decades and is still explored for new applications. They are highly versatile …

[PDF][PDF] The technologies used for develo** orally disintegrating tablets: A review

B Badgujar, A Mundada - Acta pharmaceutica, 2011 - sciendo.com
Orally disintegrating tablets (ODTs), also known as fast melts, quick melts, fast disintegrating
and orodispersible systems, have the unique property of disintegrating in the mouth in …

Microenvironmental pH modification in buccal/sublingual dosage forms for systemic drug delivery

S He, H Mu - Pharmaceutics, 2023 - mdpi.com
Many drug candidates are poorly water-soluble. Microenvironmental pH (pHM) modification
in buccal/sublingual dosage forms has attracted increasing interest as a promising …

Effect of a disintegration mechanism on wetting, water absorption, and disintegration time of orodispersible tablets

RM Pabari, Z Ramtoola - Journal of young pharmacists, 2012 - Elsevier
The aim ofthis study was to evaluate the influence of disintegration mechanism ofvarious
types of disintegrants on the absorption ratio (AR), Wetting time (WT), and disintegration time …

Formulation and evaluation of self-nanoemulsifying drug delivery system derived tablet containing sertraline

AB Nair, B Singh, J Shah, S Jacob, B Aldhubiab… - Pharmaceutics, 2022 - mdpi.com
Being a biopharmaceutics classification system class II drug, the absorption of sertraline
from the gut is mainly limited by its poor aqueous solubility. The objective of this …

Preparation and evaluation of niosome gel containing acyclovir for enhanced dermal deposition

S Jacob, AB Nair, BE Al-Dhubiab - Journal of liposome research, 2017 - Taylor & Francis
Niosomes suggest a versatile vesicle delivery system with possible transport of drugs via
topical route for skin delivery. The aim of the present research was to optimize niosome gel …

[HTML][HTML] Enhancement in antinociceptive and anti-inflammatory effects of tramadol by transdermal proniosome gel

J Shah, AB Nair, H Shah, S Jacob, TM Shehata… - Asian Journal of …, 2020 - Elsevier
Oral therapy of tramadol, an opiate analgesic, undergoes extensive hepatic metabolism and
requires frequent administration. Transdermal therapy by virtue can overcome these issues …

Compressed orally disintegrating tablets: excipients evolution and formulation strategies

A Al-Khattawi, AR Mohammed - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Orally disintegrating tablets (ODTs) have emerged as one of the novel solid
oral dosage forms with a potential to deliver a wide range of drug candidates to both …

Prevention of rat liver fibrosis by selective targeting of hepatic stellate cells using hesperidin carriers

MA Morsy, AB Nair - International journal of pharmaceutics, 2018 - Elsevier
Therapeutic efficacy of antifibrotic drugs can be improved by targeting hepatic stellate cells
(HSCs). This study investigated the prospect of develo** a carrier system for the effective …