[HTML][HTML] Reduction of daily-use parabens and phthalates reverses accumulation of cancer-associated phenotypes within disease-free breast tissue of study subjects
SH Dairkee, DH Moore, MG Luciani, N Anderle… - Chemosphere, 2023 - Elsevier
Estrogenic overstimulation is carcinogenic to the human breast. Personal care products
(PCPs) commonly contain xenoestrogens (XE), such as parabens and phthalates. Here, we …
(PCPs) commonly contain xenoestrogens (XE), such as parabens and phthalates. Here, we …
Resistance mechanism to Notch inhibition and combination therapy in human T-cell acute lymphoblastic leukemia
Gain-of-function mutations in NOTCH1 are among the most frequent genetic alterations in T-
cell acute lymphoblastic leukemia (T-ALL), highlighting the Notch signaling pathway as a …
cell acute lymphoblastic leukemia (T-ALL), highlighting the Notch signaling pathway as a …
PIK3CA mutation fortifies molecular determinants for immune signaling in vascular cancers
Angiosarcomas are a group of vascular cancers that form malignant blood vessels. These
malignancies are seemingly inflamed primarily due to their pathognomonic nature, which …
malignancies are seemingly inflamed primarily due to their pathognomonic nature, which …
Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3
Squamous cell lung cancer maintains its growth through elevated glucose consumption, but
selective glucose consumption inhibitors are lacking. Here, we discovered using a high …
selective glucose consumption inhibitors are lacking. Here, we discovered using a high …
PI3King the environment for growth: PI3K activation drives transcriptome changes that support oncogenic growth
SE Claridge, BD Hopkins - Cancer research, 2022 - AACR
PI3K signaling plays an integral role in cells, coordinating the necessary alterations in
cellular metabolism and programs to support survival and proliferation. In the first genome …
cellular metabolism and programs to support survival and proliferation. In the first genome …
Author Spotlight: Exploring Salidroside's Molecular Mechanisms in Breast Cancer Treatment
L Cui, C Ye, T Luo, H Jiang, B Lai, H Wang… - JoVE (Journal of …, 2023 - jove.com
Salidroside (Sal) contains anti-carcinogenic, anti-hypoxic, and anti-inflammatory
pharmacological activities. However, its underlying anti-breast cancer mechanisms have …
pharmacological activities. However, its underlying anti-breast cancer mechanisms have …
Resistance mechanism to Notch inhibition and combination therapy in human T cell acute lymphoblastic leukemia
F Radtke, L Cao, GR Buendía, N Fournier, Y Liu… - 2023 - researchsquare.com
Gain-of-function mutations in NOTCH1 are among the most frequent genetic alterations in T
cell acute lymphoblastic leukemia (T-ALL), making the Notch signaling pathway a promising …
cell acute lymphoblastic leukemia (T-ALL), making the Notch signaling pathway a promising …