The BCL-2 family of proteins integrates signals that trigger either cell survival or apoptosis.
The balance between pro-survival and pro-apoptotic proteins is important for tissue …

Objectives We assessed the association between acculturation and health-related quality of
life (HRQoL) among persons with a Turkish migrant background in Germany. Methods 1226 …

Programmed cell death (PCD) has been identified as a key process in the metamorphic
transition of indirectly develo** organisms such as frogs and insects. Many marine …

Peimine (PM), a natural product extracted from Fritillaria, has anti‐inflammatory, drug
resistance reversal, and other pharmacological effects. The purpose of this study was to …

γ-herpesviruses (γHVs) are common human pathogens that encode homologs of the anti-
apoptotic cellular Bcl-2 proteins, which are critical to viral reactivation and oncogenic …

B-cell lymphoma-extra large (Bcl-xL) is an anti-apoptotic member of the Bcl2 family of
proteins, which supports neurite outgrowth and neurotransmission by improving …

Nucleic acid-programmed reactions find application in drug screening and nucleic acid
diagnosis, and offer prospects for a RNA-sensitive prodrug approach. We aim for the …

Protein-protein interactions play an essential role in many biological processes, and their
perturbation is a major cause of disease. The use of small molecules to modulate them is …

Bcl-XL, an antiapoptotic Bcl-2 family protein, plays a central role in the regulation of the
apoptotic pathway. Heterodimerization of the antiapoptotic Bcl-2 family proteins with the …

B-cell lymphoma 2 (Bcl-2) proteins are central, conserved regulators of apoptosis. Bcl-2
family function is regulated by binding interactions between the Bcl-2 homology 3 (BH3) …