Trypstatin as a Novel TMPRSS2 Inhibitor with Broad-Spectrum 1 Efficacy Against Corona and Influenza Viruses

J Lawrenz, L Wettstein, A Rodriguez Alfonso… - bioRxiv, 2025 - biorxiv.org
Respiratory viruses, such as SARS-CoV-2 and influenza, exploit host proteases like
TMPRSS2 for entry, making TMPRSS2 a prime antiviral target. Here, we report the …