Bacterial chitin degradation—mechanisms and ecophysiological strategies

S Beier, S Bertilsson - Frontiers in microbiology, 2013 - frontiersin.org
Chitin is one the most abundant polymers in nature and interacts with both carbon and
nitrogen cycles. Processes controlling chitin degradation are summarized in reviews …

Structural and sequence-based classification of glycoside hydrolases

B Henrissat, G Davies - Current opinion in structural biology, 1997 - Elsevier
The diversity of oligo-and polysaccharides provides an abundance of biological roles for
these carbohydrates. The enzymes hydrolysing these compounds, the glycoside hydrolases …

Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases

H Merzendorfer, L Zimoch - Journal of Experimental Biology, 2003 - journals.biologists.com
Chitin is one of the most important biopolymers in nature. It is mainly produced by fungi,
arthropods and nematodes. In insects, it functions as scaffold material, supporting the …

Microbial enzymes—an overview

RS Singh, T Singh, A Pandey - Advances in enzyme technology, 2019 - Elsevier
People have exploited the biocatalytic potential of microorganisms for centuries to produce
wine, vinegar, bread, and so forth without understanding their biochemical basis. Microbial …

Chitinases from bacteria to human: properties, applications, and future perspectives

AS Rathore, RD Gupta - Enzyme research, 2015 - Wiley Online Library
Chitin is the second most plenteous polysaccharide in nature after cellulose, present in cell
walls of several fungi, exoskeletons of insects, and crustacean shells. Chitin does not …

Biotechnological aspects of chitinolytic enzymes: a review

N Dahiya, R Tewari, GS Hoondal - Applied microbiology and …, 2006 - Springer
Abstract Chitin and chitinases (EC 3.2. 1.14) have an immense potential. Chitinolytic
enzymes have wide-ranging applications such as preparation of pharmaceutically important …

Recent insights into inhibition, structure, and mechanism of configuration‐retaining glycosidases

TD Heightman, AT Vasella - Angewandte Chemie International …, 1999 - Wiley Online Library
Abstract Not “from above”, but “from the side”: Configuration‐retaining β‐glycosidases
protonate their substrate either anti or syn to the endocyclic C1− O bond as the first step in …

Stereochemistry of chitin hydrolysis by a plant chitinase/lysozyme and x-ray structure of a complex with allosamidin evidence for substrate assisted catalysis

AC Terwisscha van Scheltinga, S Armand, KH Kalk… - Biochemistry, 1995 - ACS Publications
Revised Manuscript Received October 23, 1995® abstract: The plant enzyme hevamine has
both chitinase and lysozyme activity. HPLC analysis of the products of the hydrolysis of …

Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay–Sachs disease

I Tews, A Perrakis, A Oppenheim, Z Dauter… - Nature structural …, 1996 - nature.com
Chitin, the second most abundant polysaccharide on earth, is degraded by chitinases and
chitobiases. The structure of Serratia marcescens chitobiase has been refined at 1.9 Å …

Rapid evolution in plant chitinases: molecular targets of selection in plant-pathogen coevolution

JG Bishop, AM Dean… - Proceedings of the …, 2000 - National Acad Sciences
Many pathogen recognition genes, such as plant R-genes, undergo rapid adaptive
evolution, providing evidence that these genes play a critical role in plant-pathogen …