Introduction: Poly (ϵ-caprolactone)(PCL), a biodegradable and biocompatible polymer, is
useful to encapsulate a wide range of drugs making it an interesting material for the …

Resveratrol and curcumin are natural antioxidants found in the human diet that have been
used in the prevention and treatment of different diseases associated with oxidative stress …

Drug delivery to the brain represents a challenge, especially in the therapy of central
nervous system malignancies. Simvastatin (SVT), as with other statins, has shown potential …

The human papillomavirus (HPV) infection, which is strongly related to cervical cancer, can
be reduced by the topical application of imiquimod. Some strategies have been used to …

Polyphenols such as curcumin (Cur) and resveratrol (Res) have been recently shown to
have potential to inhibit proliferation of highly aggressive melanoma cells. This study was …

Abstract Treatment of bacterial airway infections is essential for cystic fibrosis therapy.
However, effectiveness of antibacterial treatment is limited as bacteria inside the mucus are …

Carvedilol is a drug used to treat heart failure, hypertension, and coronary artery diseases.
However, it has low oral bioavailability (25–35%) due to its high first-pass hepatic …

Dermatological applications of phloretin are restricted by its poor aqueous solubility.
Nanotechnology has been proposed as strategy to increase the apparent drug solubility in …

Caenorhabditis elegans is an alternative in vivo model that is being successfully used to
assess the pharmacological and toxic effects of drugs. The exponential growth of …

Glioblastoma is the most common and lethal malignant brain tumor. Despite simvastatin
(SVT) showing potential anticancer properties, its antitumoral effect against glioblastoma …