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Inhibitory control of the excitatory/inhibitory balance in psychiatric disorders
Neuronal networks consist of different types of neurons that all play their own role in order to
maintain proper network function. The two main types of neurons segregate in excitatory and …
maintain proper network function. The two main types of neurons segregate in excitatory and …
Neuronal circuits in barrel cortex for whisker sensory perception
The array of whiskers on the snout provides rodents with tactile sensory information relating
to the size, shape and texture of objects in their immediate environment. Rodents can use …
to the size, shape and texture of objects in their immediate environment. Rodents can use …
Parallel emergence of stable and dynamic memory engrams in the hippocampus
During our daily life, we depend on memories of past experiences to plan future behaviour.
These memories are represented by the activity of specific neuronal groups or 'engrams' …
These memories are represented by the activity of specific neuronal groups or 'engrams' …
Vision and locomotion shape the interactions between neuron types in mouse visual cortex
Cortical computation arises from the interaction of multiple neuronal types, including
pyramidal (Pyr) cells and interneurons expressing Sst, Vip, or Pvalb. To study the circuit …
pyramidal (Pyr) cells and interneurons expressing Sst, Vip, or Pvalb. To study the circuit …
Prefrontal somatostatin interneurons encode fear memory
Theories stipulate that memories are encoded within networks of cortical projection neurons.
Conversely, GABAergic interneurons are thought to function primarily to inhibit projection …
Conversely, GABAergic interneurons are thought to function primarily to inhibit projection …
Specialized connectivity of molecular layer interneuron subtypes leads to disinhibition and synchronous inhibition of cerebellar Purkinje cells
Molecular layer interneurons (MLIs) account for approximately 80% of the inhibitory
interneurons in the cerebellar cortex and are vital to cerebellar processing. MLIs are thought …
interneurons in the cerebellar cortex and are vital to cerebellar processing. MLIs are thought …
Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition
Social competition plays a pivotal role in determining individuals' social status. While the
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …
Cortex-wide response mode of VIP-expressing inhibitory neurons by reward and punishment
Neocortex is classically divided into distinct areas, each specializing in different function, but
all could benefit from reinforcement feedback to inform and update local processing. Yet it …
all could benefit from reinforcement feedback to inform and update local processing. Yet it …
Distinct and dynamic ON and OFF neural ensembles in the prefrontal cortex code social exploration
The medial prefrontal cortex (mPFC) is important for social behavior, but the mechanisms by
which mPFC neurons code real-time social exploration remain largely unknown. Here we …
which mPFC neurons code real-time social exploration remain largely unknown. Here we …
[HTML][HTML] Control of fear by discrete prefrontal GABAergic populations encoding valence-specific information
Neurons activated by learning have been ascribed the unique potential to encode memory,
but the functional contribution of discrete cell types remains poorly understood. In particular …
but the functional contribution of discrete cell types remains poorly understood. In particular …