Nanotechnology approaches for global infectious diseases

AR Kirtane, M Verma, P Karandikar, J Furin… - Nature …, 2021 - nature.com
Infectious diseases are a major driver of morbidity and mortality globally. Treatment of
malaria, tuberculosis and human immunodeficiency virus infection are particularly …

The advanced role of carbon quantum dots in nanomedical applications

P Devi, S Saini, KH Kim - Biosensors and Bioelectronics, 2019 - Elsevier
Carbon quantum dots (CQDs) have emerged as a potential material in the diverse fields of
biomedical applications due to their numerous advantageous properties including …

Biofilm heterogeneity-adaptive photoredox catalysis enables red light-triggered nitric oxide release for combating drug-resistant infections

J Cheng, G Gan, S Zheng, G Zhang, C Zhu… - Nature …, 2023 - nature.com
The formation of biofilms is closely associated with persistent and chronic infections, and
physiological heterogeneity such as pH and oxygen gradients renders biofilms highly …

Approaches for the inhibition and elimination of microbial biofilms using macromolecular agents

LD Blackman, Y Qu, P Cass, KES Locock - Chemical Society Reviews, 2021 - pubs.rsc.org
Biofilms are complex three-dimensional structures formed at interfaces by the vast majority
of bacteria and fungi. These robust communities have an important detrimental impact on a …

Recent advances in the development of nitric oxide-releasing biomaterials and their application potentials in chronic wound healing

M Wu, Z Lu, K Wu, C Nam, L Zhang… - Journal of Materials …, 2021 - pubs.rsc.org
Chronic wounds, such as pressure ulcers, vascular ulcers and diabetic foot ulcers (DFUs),
often stay in a state of pathological inflammation and suffer from persistent infection, excess …

Star polymers: Advances in biomedical applications

W Wu, W Wang, J Li - Progress in Polymer Science, 2015 - Elsevier
Over the past decade, star polymers have been widely used in biomedical applications such
as drug delivery, gene delivery, tissue engineering, diagnosis, medical devices, and …

Drug delivery strategies for antibiofilm therapy

V Choi, JL Rohn, P Stoodley, D Carugo… - Nature Reviews …, 2023 - nature.com
Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …

Advanced nitric oxide donors: Chemical structure of NO drugs, NO nanomedicines and biomedical applications

Y Yang, Z Huang, LL Li - Nanoscale, 2021 - pubs.rsc.org
Nitric oxide (NO), as an endogenous diatomic molecule, plays a key regulatory role in many
physiological and pathological processes. This diatomic free radical has been shown to …

A multinuclear metal complex based DNase‐mimetic artificial enzyme: matrix cleavage for combating bacterial biofilms

Z Chen, H Ji, C Liu, W Bing, Z Wang… - Angewandte Chemie, 2016 - Wiley Online Library
Extracellular DNA (eDNA) is an essential structural component during biofilm formation,
including initial bacterial adhesion, subsequent development, and final maturation. Herein …

Synthetic antimicrobial polymers in combination therapy: tackling antibiotic resistance

R Namivandi-Zangeneh, EHH Wong… - ACS Infectious …, 2021 - ACS Publications
Antibiotic resistance is a critical global healthcare issue that urgently needs new effective
solutions. While small molecule antibiotics have been safeguarding us for nearly a century …