Computational psychiatry: from synapses to sentience

K Friston - Molecular psychiatry, 2023 - nature.com
This review considers computational psychiatry from a particular viewpoint: namely, a
commitment to explaining psychopathology in terms of pathophysiology. It rests on the …

[HTML][HTML] Interoceptive pathways to understand and treat mental health conditions

CL Nord, SN Garfinkel - Trends in Cognitive Sciences, 2022 - cell.com
An increasing recognition that brain and body are dynamically coupled has enriched our
scientific understanding of mental health conditions. Peripheral signals interact centrally to …

[HTML][HTML] Towards a comprehensive assessment of interoception in a multi-dimensional framework

C Suksasilp, SN Garfinkel - Biological Psychology, 2022 - Elsevier
Interoception has historically been assessed using behavioural tests of accuracy, self-report
measures or through the characterisation of neural signals underlying interoceptive …

[HTML][HTML] A step-by-step tutorial on active inference and its application to empirical data

R Smith, KJ Friston, CJ Whyte - Journal of mathematical psychology, 2022 - Elsevier
The active inference framework, and in particular its recent formulation as a partially
observable Markov decision process (POMDP), has gained increasing popularity in recent …

The empirical status of predictive coding and active inference

R Hodson, M Mehta, R Smith - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Research on predictive processing models has focused largely on two specific algorithmic
theories: Predictive Coding for perception and Active Inference for decision-making. While …

[HTML][HTML] The heart rate discrimination task: A psychophysical method to estimate the accuracy and precision of interoceptive beliefs

N Legrand, N Nikolova, C Correa, M Brændholt… - Biological …, 2022 - Elsevier
Interoception-the physiological sense of our inner bodies-has risen to the forefront of
psychological and psychiatric research. Much of this research utilizes tasks that attempt to …

In the body's eye: the computational anatomy of interoceptive inference

M Allen, A Levy, T Parr, KJ Friston - PLoS Computational Biology, 2022 - journals.plos.org
A growing body of evidence highlights the intricate linkage of exteroceptive perception to the
rhythmic activity of the visceral body. In parallel, interoceptive inference theories of affective …

Interoception of breathing and its relationship with anxiety

OK Harrison, L Köchli, S Marino, R Luechinger… - Neuron, 2021 - cell.com
Interoception, the perception of internal bodily states, is thought to be inextricably linked to
affective qualities such as anxiety. Although interoception spans sensory to metacognitive …

[HTML][HTML] Beyond simple laboratory studies: develo** sophisticated models to study rich behavior

A Maselli, J Gordon, M Eluchans, GL Lancia… - Physics of Life …, 2023 - Elsevier
Psychology and neuroscience are concerned with the study of behavior, of internal cognitive
processes, and their neural foundations. However, most laboratory studies use constrained …

Simulating homeostatic, allostatic and goal-directed forms of interoceptive control using active inference

A Tschantz, L Barca, D Maisto, CL Buckley, AK Seth… - Biological …, 2022 - Elsevier
The adaptive regulation of bodily and interoceptive parameters, such as body temperature,
thirst and hunger is a central problem for any biological organism. Here, we present a series …