Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

Matrix metalloproteinases in chemoresistance: regulatory roles, molecular interactions, and potential inhibitors

BXJ Tune, MS Sim, CL Poh, RM Guad… - Journal of …, 2022 - Wiley Online Library
Cancer is one of the major causes of death worldwide. Its treatments usually fail when the
tumor has become malignant and metastasized. Metastasis is a key source of cancer …

Inflammation and matrix metalloproteinase 9 (Mmp‐9) regulate photoreceptor regeneration in adult zebrafish

NJ Silva, M Nagashima, J Li, L Kakuk‐Atkins… - Glia, 2020 - Wiley Online Library
Brain injury activates complex inflammatory signals in dying neurons, surviving neurons,
and glia. Here, we establish that inflammation regulates the regeneration of photoreceptors …

Cannabinoid signaling promotes the de‐differentiation and proliferation of Müller glia‐derived progenitor cells

WA Campbell, S Blum, A Reske, T Hoang… - Glia, 2021 - Wiley Online Library
Endocannabinoids (eCB) are lipid‐based neurotransmitters that are known to influence
synaptic function in the visual system. eCBs are also known to suppress neuroinflammation …

[HTML][HTML] Repopulated retinal microglia promote Müller glia reprogramming and preserve visual function in retinal degenerative mice

X Cheng, H Gao, Z Tao, Z Yin, Z Cha, X Huang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Rationale: Müller glia (MG) play a key role in maintaining homeostasis of the retinal
microenvironment. In zebrafish, MG reprogram into retinal progenitors and repair the injured …

Regulating the formation of Müller glia‐derived progenitor cells in the retina

OB Taylor, HM El‐Hodiri, I Palazzo, L Todd, AJ Fischer - Glia, 2025 - Wiley Online Library
We summarize recent findings in different animal models regarding the different cell‐
signaling pathways and gene networks that influence the reprogramming of Müller glia into …

Nuclear Factor I in neurons, glia and during the formation of Müller glia‐derived progenitor cells in avian, porcine and primate retinas

HM El‐Hodiri, WA Campbell, LE Kelly… - Journal of …, 2022 - Wiley Online Library
The regenerative potential of Müller glia (MG) is extraordinary in fish, poor in chick and
terrible in mammals. In the chick model, MG readily reprogram into proliferating Müller glia …

Chromatin access regulates the formation of Müller glia‐derived progenitor cells in the retina

WA Campbell, HM El‐Hodiri, D Torres, EC Hawthorn… - Glia, 2023 - Wiley Online Library
Chromatin access and epigenetic control over gene expression play important roles in
regulating developmental processes. However, little is known about how chromatin access …

Fatty acid-binding proteins and fatty acid synthase influence glial reactivity and promote the formation of Müller glia-derived progenitor cells in the chick retina

WA Campbell, A Tangeman, HM El-Hodiri… - …, 2022 - journals.biologists.com
ABSTRACT A recent comparative transcriptomic study of Müller glia (MG) in vertebrate
retinas revealed that fatty acid binding proteins (FABPs) are among the most highly …

Heparin-binding epidermal growth factor and fibroblast growth factor 2 rescue Müller glia-derived progenitor cell formation in microglia-and macrophage-ablated chick …

HM El-Hodiri, JR Bentley, AG Reske… - …, 2023 - journals.biologists.com
Recent studies have demonstrated the impact of pro-inflammatory signaling and reactive
microglia/macrophages on the formation of Müller glial-derived progenitor cells (MGPCs) in …