The gut microbiota in obesity and weight management: microbes as friends or foe?

M Van Hul, PD Cani - Nature Reviews Endocrinology, 2023 - nature.com
Obesity is caused by a long-term difference between energy intake and expenditure—an
imbalance that is seemingly easily restored by increasing exercise and reducing caloric …

Key determinants of success in fecal microbiota transplantation: From microbiome to clinic

S Porcari, N Benech, M Valles-Colomer, N Segata… - Cell host & …, 2023 - cell.com
Fecal microbiota transplantation (FMT) has achieved satisfactory results in preventing the
recurrence of Clostridioides difficile infection, but these positive outcomes have only been …

Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders

A Metwaly, S Reitmeier, D Haller - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

Pathogenesis and treatment of non-alcoholic steatohepatitis and its fibrosis

KC Lee, PS Wu, HC Lin - Clinical and molecular hepatology, 2022 - pmc.ncbi.nlm.nih.gov
The initial presentation of non-alcoholic steatohepatitis (NASH) is hepatic steatosis. The
dysfunction of lipid metabolism within hepatocytes caused by genetic factors, diet, and …

Dietary regulation in health and disease

Q Wu, ZJ Gao, X Yu, P Wang - Signal Transduction and Targeted …, 2022 - nature.com
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

[HTML][HTML] Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics

D Li, Y Li, S Yang, J Lu, X **, M Wu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The prevalence of metabolic diseases, including obesity, dyslipidemia, type 2 diabetes
mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD), is a severe burden in human …

Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a

Y Sun, Q Nie, S Zhang, H He, S Zuo, C Chen… - Nature …, 2023 - nature.com
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control
study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis …

The potential of tailoring the gut microbiome to prevent and treat cardiometabolic disease

RM Chakaroun, LM Olsson, F Bäckhed - Nature Reviews Cardiology, 2023 - nature.com
Despite milestones in preventive measures and treatment, cardiovascular disease (CVD)
remains associated with a high burden of morbidity and mortality. The protracted nature of …

Health improvements of type 2 diabetic patients through diet and diet plus fecal microbiota transplantation

L Su, Z Hong, T Zhou, Y Jian, M Xu, X Zhang, X Zhu… - Scientific reports, 2022 - nature.com
Abstract Type 2 diabetes (T2D) is a major public health problem, and gut microbiota
dysbiosis has been implicated in the emergence of T2D in humans. Dietary interventions …

[HTML][HTML] The role of diet in sha** human gut microbiota

E Rinninella, E Tohumcu, P Raoul, M Fiorani… - Best Practice & …, 2023 - Elsevier
Gut microbiota plays a fundamental role within human health, and exerts key functions
within the human body. Diet is one of the most powerful modulators of gut microbiota …