Molecular mechanisms of antibiotic resistance revisited
Antibiotic resistance is a global health emergency, with resistance detected to all antibiotics
currently in clinical use and only a few novel drugs in the pipeline. Understanding the …
currently in clinical use and only a few novel drugs in the pipeline. Understanding the …
The population genetics of pathogenic Escherichia coli
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …
The source of the Black Death in fourteenth-century central Eurasia
The origin of the medieval Black Death pandemic (ad 1346–1353) has been a topic of
continuous investigation because of the pandemic's extensive demographic impact and long …
continuous investigation because of the pandemic's extensive demographic impact and long …
INfrastructure for a PHAge REference database: identification of large-scale biases in the current collection of cultured phage genomes
Background: With advances in sequencing technology and decreasing costs, the number of
phage genomes that have been sequenced has increased markedly in the past decade …
phage genomes that have been sequenced has increased markedly in the past decade …
[HTML][HTML] The potential of using E. coli as an indicator for the surveillance of antimicrobial resistance (AMR) in the environment
Highlights•There is an urgent need for environmental Antimicrobial resistance (AMR)
monitoring.•E. coli are part of established human and livestock AMR surveillance …
monitoring.•E. coli are part of established human and livestock AMR surveillance …
[HTML][HTML] Global spread of Salmonella Enteritidis via centralized sourcing and international trade of poultry breeding stocks
A pandemic of Salmonella enterica serotype Enteritidis emerged in the 1980s due to
contaminated poultry products. How Salmonella Enteritidis rapidly swept through continents …
contaminated poultry products. How Salmonella Enteritidis rapidly swept through continents …
Shiga toxin-associated hemolytic uremic syndrome: A narrative review
A Joseph, A Cointe, P Mariani Kurkdjian, C Rafat… - Toxins, 2020 - mdpi.com
The severity of human infection by one of the many Shiga toxin-producing Escherichia coli
(STEC) is determined by a number of factors: the bacterial genome, the capacity of human …
(STEC) is determined by a number of factors: the bacterial genome, the capacity of human …
Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes
Background: The Global Typhoid Genomics Consortium was established to bring together
the typhoid research community to aggregate and analyse Salmonella enterica serovar …
the typhoid research community to aggregate and analyse Salmonella enterica serovar …
Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene blaNDM
The mobile resistance gene bla NDM encodes the NDM enzyme which hydrolyses
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …
[HTML][HTML] Genomic epidemiology of global carbapenemase-producing Escherichia coli, 2015–2017
We describe the global molecular epidemiology of 229 carbapenemase-producing
Escherichia coli in 36 countries during 2015–2017. Common carbapenemases were …
Escherichia coli in 36 countries during 2015–2017. Common carbapenemases were …