DNA as a universal chemical substrate for computing and data storage

S Yang, BWA Bögels, F Wang, C Xu, H Dou… - Nature Reviews …, 2024 - nature.com
DNA computing and DNA data storage are emerging fields that are unlocking new
possibilities in information technology and diagnostics. These approaches use DNA …

Molecular computation for molecular classification

C Kieffer, AJ Genot, Y Rondelez, G Gines - Advanced Biology, 2023 - Wiley Online Library
DNA as an informational polymer has, for the past 30 years, progressively become an
essential molecule to rationally build chemical reaction networks endowed with powerful …

Orthogonal enzyme-driven timers for DNA strand displacement reactions

J Bucci, P Irmisch, E Del Grosso… - Journal of the …, 2022 - ACS Publications
Here, we demonstrate a strategy to rationally program a delayed onset of toehold-mediated
DNA strand displacement reactions (SDRs). The approach is based on blocker strands that …

Efficient intracellular MicroRNA imaging based on the localized and self-sustainable catalytic DNA assembly circuit

C **e, R Li, X Gong, Q Zhang, Y Zhang… - Analytical …, 2023 - ACS Publications
Building dynamic biological networks, especially DNA circuits, has provided a powerful
prospect for exploring the intrinsic regulation processes of live cells. Nevertheless, for …

Temporally controlled multistep division of DNA droplets for dynamic artificial cells

T Maruyama, J Gong, M Takinoue - Nature Communications, 2024 - nature.com
Synthetic droplets mimicking bio-soft matter droplets formed via liquid-liquid phase
separation (LLPS) in living cells have recently been employed in nanobiotechnology for …

DNAzyme-based dissipative DNA strand displacement for constructing temporal logic gates

M Hu, X Li, J Wu, M Yang, T Wu - Acs Nano, 2024 - ACS Publications
Toehold-mediated DNA strand displacement is the foundation of dynamic DNA
nanotechnology, encompassing a wide range of tools with diverse functions, dynamics, and …

Amp aptamer programs DNA tile cohesion without canonical base pairing

Z Zhang, J **, VE Paluzzi, Z **, Y Wen… - Journal of the …, 2023 - ACS Publications
Tile-based DNA self-assembly provides a versatile approach for the construction of a wide
range of nanostructures for various applications such as nanomedicine and advanced …

A visual DNA compilation of Rössler system and its application in color image encryption

C Zou, L Wang - Chaos, Solitons & Fractals, 2023 - Elsevier
This paper proposes the use of visual DNA compilation for the Rössler chaotic system in the
context of semi-synthetic biology, which has promising prospects for the development of next …

Series or parallel toehold-mediated strand displacement and its application in circular RNA detection and logic gates

S Bai, B Xu, J Wu, G **e - Biosensors and Bioelectronics, 2023 - Elsevier
Toehold-mediated strand displacement (TMSD) is widely employed in constructing a wide
range of chemical reaction networks. In TMSD, single-stranded DNA or RNA can fold back …

Tuning strand displacement kinetics enables programmable ZTP riboswitch dynamic range in vivo

DZ Bushhouse, JB Lucks - Nucleic acids research, 2023 - academic.oup.com
A large body of work has shown that transcriptional riboswitches function through internal
strand displacement mechanisms that guide the formation of alternative structures which …