Multimodal fusion in neuroimaging combines data from multiple imaging modalities to
overcome the fundamental limitations of individual modalities. Neuroimaging fusion can …

Abstract Background The glutamate (Glu) and gamma aminobutyric acid (GABA)
hypotheses of schizophrenia were proposed in the 1980s. However, current findings on …

Glutamatergic and GABAergic dysfunction are implicated in the pathophysiology of
schizophrenia. Previous work has shown relationships between glutamate, GABA, and brain …

Epidemiologic, genetic, and neurobiological studies suggest considerable overlap between
schizophrenia and mood disorders. Importantly, both disorders are associated with a broad …

Multimodal neuroimaging studies combining proton magnetic resonance spectroscopy (1H-
MRS) to quantify GABA and/or glutamate concentrations and functional magnetic resonance …

A subgroup of patients with schizophrenia is believed to have aberrant excess of glutamate
in the frontal cortex; this subgroup is thought to show poor response to first-line antipsychotic …

Abstract Proton (1 H) Magnetic Resonance Spectroscopy (MRS) is a non-invasive tool
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …

Over the last three decades there has been an accumulation of Magnetic Resonance
Imaging (MRI) studies reporting that aberrant functional networks may underlie cognitive …

Background Converging lines of evidence point to hippocampal dysfunction in
schizophrenia. It is thought that hippocampal dysfunction spreads across hippocampal …

Glaucoma is an age-related neurodegenerative disease of the visual system, affecting both
the eye and the brain. Yet its underlying metabolic mechanisms and neurobehavioral …