Towards a genomics-informed, real-time, global pathogen surveillance system
Abstract The recent Ebola and Zika epidemics demonstrate the need for the continuous
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
Viral phylodynamics
Viral phylodynamics is defined as the study of how epidemiological, immunological, and
evolutionary processes act and potentially interact to shape viral phylogenies. Since the …
evolutionary processes act and potentially interact to shape viral phylogenies. Since the …
Early phylogenetic estimate of the effective reproduction number of SARS‐CoV‐2
A Lai, A Bergna, C Acciarri, M Galli… - Journal of medical …, 2020 - Wiley Online Library
To reconstruct the evolutionary dynamics of the 2019 novel‐coronavirus recently causing an
outbreak in Wuhan, China, 52 SARS‐CoV‐2 genomes available on 4 February 2020 at …
outbreak in Wuhan, China, 52 SARS‐CoV‐2 genomes available on 4 February 2020 at …
Birth–death skyline plot reveals temporal changes of epidemic spread in HIV and hepatitis C virus (HCV)
Phylogenetic trees can be used to infer the processes that generated them. Here, we
introduce a model, the Bayesian birth–death skyline plot, which explicitly estimates the rate …
introduce a model, the Bayesian birth–death skyline plot, which explicitly estimates the rate …
Bayesian coalescent inference of past population dynamics from molecular sequences
We introduce the Bayesian skyline plot, a new method for estimating past population
dynamics through time from a sample of molecular sequences without dependence on a …
dynamics through time from a sample of molecular sequences without dependence on a …
How generation intervals shape the relationship between growth rates and reproductive numbers
Mathematical models of transmission have become invaluable management tools in
planning for the control of emerging infectious diseases. A key variable in such models is the …
planning for the control of emerging infectious diseases. A key variable in such models is the …
Unifying the epidemiological and evolutionary dynamics of pathogens
A key priority for infectious disease research is to clarify how pathogen genetic variation,
modulated by host immunity, transmission bottlenecks, and epidemic dynamics, determines …
modulated by host immunity, transmission bottlenecks, and epidemic dynamics, determines …
Perspectives on the basic reproductive ratio
JM Heffernan, RJ Smith… - Journal of the Royal …, 2005 - royalsocietypublishing.org
The basic reproductive ratio, R 0, is defined as the expected number of secondary infections
arising from a single individual during his or her entire infectious period, in a population of …
arising from a single individual during his or her entire infectious period, in a population of …
[PDF][PDF] Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
International standardization and coordination of the nomenclature of variants of hepatitis C
virus (HCV) is increasingly needed as more is discovered about the scale of HCV‐related …
virus (HCV) is increasingly needed as more is discovered about the scale of HCV‐related …
The global epidemiology of hepatocellular carcinoma: present and future
KA McGlynn, WT London - Clinics in liver disease, 2011 - liver.theclinics.com
On the global scale, primary liver cancer is a major contributor to both cancer incidence and
mortality. It is the sixth most commonly occurring cancer in the world and the third largest …
mortality. It is the sixth most commonly occurring cancer in the world and the third largest …