[HTML][HTML] From Cellular to Metabolic: Advances in Imaging of Inherited Retinal Diseases

DC Parameswarappa, A Kulkarni, NK Sahoo… - Diagnostics, 2024 - mdpi.com
Background: Inherited retinal diseases (IRDs) are a genetically complex group of disorders,
usually resulting in progressive vision loss due to retinal degeneration. Traditional imaging …

Two-photon excitation fluorescence in ophthalmology: safety and improved imaging for functional diagnostics

V Kaushik, M Dąbrowski, L Gessa, N Kumar… - Frontiers in …, 2024 - frontiersin.org
Two-photon excitation fluorescence (TPEF) is emerging as a powerful imaging technique
with superior penetration power in scattering media, allowing for functional imaging of …

Light-adapted flicker-optoretinography based on raster-scan optical coherence tomography towards clinical translation

Z Gong, Y Shi, J Liu, R Sabesan… - Biomedical Optics …, 2024 - opg.optica.org
Optoretinography (ORG) is a promising non-invasive and objective technique for assessing
retinal function by measuring its response to light stimulation. Optical coherence tomography …

Intrinsic signal optoretinography revealing AD-induced retinal photoreceptor hyperexcitability before a detectable morphological abnormality

G Ma, TH Kim, T Son, J Ding, S Ahmed, T Adejumo… - Optics letters, 2023 - opg.optica.org
Neuronal hyperexcitability promises an early biomarker of Alzheimer's disease (AD).
However, in vivo detection of neuronal hyperexcitability in the brain is technically …

Rotational distortion and compensation in optical coherence tomography with anisotropic pixel resolution

G Ma, T Son, T Adejumo, X Yao - Bioengineering, 2023 - mdpi.com
Accurate image registration is essential for eye movement compensation in optical
coherence tomography (OCT) and OCT angiography (OCTA). The spatial resolution of an …

[HTML][HTML] Optical Coherence Tomography Split-Spectrum Amplitude-Decorrelation Optoretinography Detects Early Central Cone Photoreceptor Dysfunction in Retinal …

N Wongchaisuwat, A Amato, P Yang… - … Vision Science & …, 2024 - jov.arvojournals.org
Purpose: To investigate if split-spectrum amplitude-decorrelation optoretinography
(SSADOR) can detect and measure macular cone dysfunction in inherited retinal …

[HTML][HTML] The impact of photopigment bleaching on the human rod photoreceptor subretinal space measured via optical coherence tomography

A Messner, VA Dos Santos, S Puchner… - … & Visual Science, 2024 - tvst.arvojournals.org
Purpose: The purpose of this study was to investigate rod photopigment bleaching-driven
intrinsic optical signals (IOS) in the human outer retina and its measurement repeatability …

Optical coherence tomography split-spectrum amplitude-decorrelation optoretinography

S Chen, S Ni, A Jiménez-Villar, Y Jian, Y Jia… - Optics Letters, 2023 - opg.optica.org
This pilot study reports the development of optical coherence tomography (OCT) split-
spectrum amplitude-decorrelation optoretinography (SSADOR) that measures spatially …

Polarization Assessment of Ballistically Reflected and Multiply Scattered Photons in Retinal OCT

X Yao, S Ahmed, T Son - Conference on Lasers and Electro-Optics …, 2024 - opg.optica.org
Parallel-polarization OCT primarily detects ballistically reflected photons, while cross-
polarization OCT captures multiply scattered photons. Comparative polarization …

Intrinsic signal optoretinography reveals AD-induced retinal photoreceptor hyperexcitability before detectable morphological abnormality

X Yao, G Ma, TH Kim, T Son, J Ding, S Ahmed… - 2023 - preprints.opticaopen.org
Neuronal hyperexcitability promises an early biomarker of Alzheimer's disease (AD).
However, in vivo detection of neuronal hyperexcitability in the brain is technically …