Silver coordination compounds with a number of different ligands (N-heterocyclic carbenes,
phosphines, N-heterocycles and others) possess several properties, ranging from …

There is much recent evidence showing that mitochondria play a critical role in the
regulation of apoptosis (programmed cell death), making them an attractive target for the …

Silver has been used for numerous medical conditions for centuries, however, most of the
current clinical silver agents all have their own disadvantages limiting the clinical …

Silver is proving to have a number of medicinal applications; as an antiseptic, an
antibacterial, and an anti-inflammatory, while any biological role for it is currently unknown …

The cytotoxicity and anti-tumour activity screening trials for both gold (I) and gold (III) are
summarised. Gold (I) thiolates employed clinically in the treatment of rheumatoid arthritis …

Well known for their clinical anti-arthritic properties, gold-based drugs have also attracted
interest as potential antitumor agents with gold (I) phosphine derivatives being among the …

Abstract Purpose: The lipophilic cation [Au (I)(dppe) 2]+[where dppe is 1, 2-bis
(diphenylphosphino) ethane] has previously demonstrated potent in vitro antitumour activity …

5966 2006 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Angew. Chem. Int. Ed. 2006,
45, 5966–5970 been interested in the development of AuI complexes of phosphine [2] and …

Bis-chelated gold (I) phosphine complexes have shown great potential as anticancer
agents, however, their efficacy has been limited by their high toxicity and lack of selectivity …

In this study we characterised the in vitro antitumour and hepatotoxicity profiles of a series of
Au (I) and Ag (I) bidentate phenyl and pyridyl complexes in a panel of cisplatin-resistant …