MYC-induced cancer cell energy metabolism and therapeutic opportunities
Although cancers have altered glucose metabolism, termed the Warburg effect, which
describes the increased uptake and conversion of glucose to lactate by cancer cells under …
describes the increased uptake and conversion of glucose to lactate by cancer cells under …
NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation
Cancer cell molecular mimicry of stem cells (SC) imbues neoplastic cells with enhanced
proliferative and renewal capacities. In support, numerous mediators of SC self-renewal …
proliferative and renewal capacities. In support, numerous mediators of SC self-renewal …
Histone bivalency in CNS development
K Mätlik, EE Govek, ME Hatten - Genes & Development, 2025 - genesdev.cshlp.org
Neuronal maturation is guided by changes in the chromatin landscape that control
developmental gene expression programs. Histone bivalency, the co-occurrence of …
developmental gene expression programs. Histone bivalency, the co-occurrence of …
Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer
Growth factors in tumor environments are regulators of cell survival and metastasis. Here,
we reveal the dichotomy between TGF-β superfamily growth factors BMP and TGF-β/activin …
we reveal the dichotomy between TGF-β superfamily growth factors BMP and TGF-β/activin …
[PDF][PDF] ImageJ user guide
T Ferreira, W Rasband - USA: National Institutes of Health, 2011 - researchgate.net
Given ImageJ's heavy development this guide will always remain an unfinished draft and
should be considered complementary to the remaining ImageJ documentation resources (cf …
should be considered complementary to the remaining ImageJ documentation resources (cf …
Collagen microencapsulation recapitulates mesenchymal condensation and potentiates chondrogenesis of human mesenchymal stem cells–A matrix-driven in vitro …
Mesenchymal condensation is a critical transitional stage that precedes cartilage or bone
formation. A microencapsulation technique was previously established to entrap …
formation. A microencapsulation technique was previously established to entrap …
A peptide based on homologous sequences of the β-barrel assembly machinery component BamD potentiates antibiotic susceptibility of Pseudomonas aeruginosa
N Mori, Y Ishii, K Tateda, S Kimura… - Journal of …, 2012 - academic.oup.com
Objectives The β-barrel assembly machinery (BAM) complex plays a critical role in outer
membrane protein (OMP) biogenesis. The outer membrane (OM) of Pseudomonas …
membrane protein (OMP) biogenesis. The outer membrane (OM) of Pseudomonas …
[HTML][HTML] TGF-β1-triggered BMI1 and SMAD2 cooperatively regulate miR-191 to modulate bone formation
XF Zhang, ZX Wang, BW Zhang, KP Huang… - … Therapy-Nucleic Acids, 2024 - cell.com
Transforming growth factor β 1 (TGF-β1), as the most abundant signaling molecule in bone
matrix, is essential for bone homeostasis. However, the signaling transduction of TGF-β1 in …
matrix, is essential for bone homeostasis. However, the signaling transduction of TGF-β1 in …
Blockade of MDM2 with inactive Cas9 prevents epithelial to mesenchymal transition in retinal pigment epithelial cells
B Liu, J Song, H Han, Z Hu, N Chen, J Cui… - Laboratory …, 2019 - nature.com
Epithelial to mesenchymal transition (EMT) plays an important role in the pathogenesis of
proliferative vitreoretinopathy (PVR). We aimed to demonstrate the role of mouse double …
proliferative vitreoretinopathy (PVR). We aimed to demonstrate the role of mouse double …
[HTML][HTML] Auxin-degron system identifies immediate mechanisms of OCT4
The pluripotency factor OCT4 is essential for the maintenance of naive pluripotent stem cells
in vitro and in vivo. However, the specific role of OCT4 in this process remains unknown …
in vitro and in vivo. However, the specific role of OCT4 in this process remains unknown …