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Cytomegalovirus latency and reactivation: an intricate interplay with the host immune response
CMV is an ancient herpesvirus that has co-evolved with its host over millions of years. The
236 kbp genome encodes at least 165 genes, four non-coding RNAs and 14 miRNAs. Of the …
236 kbp genome encodes at least 165 genes, four non-coding RNAs and 14 miRNAs. Of the …
BK polyomavirus: clinical aspects, immune regulation, and emerging therapies
SUMMARY BK polyomavirus (BKV) causes frequent infections during childhood and
establishes persistent infections within renal tubular cells and the uroepithelium, with …
establishes persistent infections within renal tubular cells and the uroepithelium, with …
The interplay between viral-derived miRNAs and host immunity during infection
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene
expression during cellular processes. The host-encoded miRNAs are known to modulate the …
expression during cellular processes. The host-encoded miRNAs are known to modulate the …
Human cytomegalovirus in cancer: the mechanism of HCMV-induced carcinogenesis and its therapeutic potential
C Yu, S He, W Zhu, P Ru, X Ge… - Frontiers in Cellular and …, 2023 - frontiersin.org
Cancer is one of the leading causes of death worldwide. Human cytomegalovirus (HCMV), a
well-studied herpesvirus, has been implicated in malignancies derived from breast …
well-studied herpesvirus, has been implicated in malignancies derived from breast …
Virus-encoded microRNAs: an overview and a look to the future
MicroRNAs (miRNAs) are small RNAs that play important roles in the regulation of gene
expression. First described as posttranscriptional gene regulators in eukaryotic hosts, virus …
expression. First described as posttranscriptional gene regulators in eukaryotic hosts, virus …
Viruses, microRNAs, and host interactions
One of the most significant recent advances in biomedical research has been the discovery
of the∼ 22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …
of the∼ 22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …
[HTML][HTML] Virus-encoded microRNAs
MicroRNAs (miRNAs) are the subject of enormous interest. They are small non-coding
RNAs that play a regulatory role in numerous and diverse cellular processes such as …
RNAs that play a regulatory role in numerous and diverse cellular processes such as …
Human cytomegalovirus latency: approaching the Gordian knot
Herpesviruses have evolved exquisite virus-host interactions that co-opt or evade a number
of host pathways to enable the viruses to persist. Persistence of human cytomegalovirus …
of host pathways to enable the viruses to persist. Persistence of human cytomegalovirus …
Cytomegalovirus latency and reactivation: recent insights into an age old problem
Human cytomegalovirus (HCMV) infection remains a major cause of morbidity in patient
populations. In certain clinical settings, it is the reactivation of the pre‐existing latent infection …
populations. In certain clinical settings, it is the reactivation of the pre‐existing latent infection …
Viral and cellular microRNAs as determinants of viral pathogenesis and immunity
MicroRNAs (miRNAs) have recently emerged as key posttranscriptional regulators of gene
expression in multicellular eukaryotes. It is increasingly clear that miRNAs of both viral and …
expression in multicellular eukaryotes. It is increasingly clear that miRNAs of both viral and …