Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

JD Martin, H Cabral, T Stylianopoulos… - Nature reviews Clinical …, 2020 - nature.com
Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …

Activatable fluorescent probes for real-time imaging-guided tumor therapy

QJ Duan, ZY Zhao, YJ Zhang, L Fu, YY Yuan… - Advanced Drug Delivery …, 2023 - Elsevier
Surgery and drug therapy are the two principal options for cancer treatment. However, their
clinical benefits are hindered by the difficulty of accurate location of the tumors and timely …

Nanoprobe-based molecular imaging for tumor stratification

X Ma, M Mao, J He, C Liang, HY **e - Chemical Society Reviews, 2023 - pubs.rsc.org
The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …

Active transcytosis and new opportunities for cancer nanomedicine

S Pandit, D Dutta, S Nie - Nature materials, 2020 - nature.com
New evidence suggests that the mechanism of nanoparticle entry into solid tumours may be
driven by an active process. This insight paves the way for approaches to enhance the …

Nanotechnology-based approaches overcome lung cancer drug resistance through diagnosis and treatment

J Li, L Zhu, HF Kwok - Drug Resistance Updates, 2023 - Elsevier
Lung cancer continues to be a malignant tumor with high mortality. Two obstacles interfere
with curative therapy of lung cancer:(i) poor diagnosis at the early stages, as symptoms are …

Stimuli-responsive polymeric nanoplatforms for cancer therapy

D Chang, Y Ma, X Xu, J **e, S Ju - Frontiers in bioengineering and …, 2021 - frontiersin.org
Polymeric nanoparticles have been widely used as carriers of drugs and bioimaging agents
due to their excellent biocompatibility, biodegradability, and structural versatility. The …

The role of immune checkpoint inhibitors in cancer therapy

AM Basudan - Clinics and Practice, 2022 - mdpi.com
Over the years, immune checkpoint inhibitors (CPIs) have become a powerful treatment
strategy in the field of cancer immunotherapy. In the last decade, the number of FDA …

Nanotechnology in the diagnosis and treatment of lung cancer

AM Cryer, AJ Thorley - Pharmacology & therapeutics, 2019 - Elsevier
Lung cancer is an umbrella term for a subset of heterogeneous diseases that are collectively
responsible for the most cancer-related deaths worldwide. Despite the tremendous progress …

Nanomedicines inhibiting tumor metastasis and recurrence and their clinical applications

X Kong, R Cheng, J Wang, Y Fang, KC Hwang - Nano Today, 2021 - Elsevier
Tumor metastasis and recurrence is one of the biggest problems in curing cancers. Due to
the difficulty in complete removal of the primary tumor in traditional surgeries and the poor …