Alzheimer's disease (AD) accounts for most dementia cases, but we lack a complete
understanding of the mechanisms responsible for the core pathology associated with the …

Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …

This study aimed to investigate the anti-neuropathic pain activity and its underlying
molecular mechanism of Ajugarin-I (Aju-I) in a rat model of diabetic neuropathic pain. The …

Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central
nervous system (CNS) that remains incurable. Withametelin (WMT), a phytosterol, showed …

Tannic acid (TA) is a natural compound present abundantly in fruit such as grapes and
green tea. In this study, we have evaluated the therapeutic efficacy of TA against …

Hepatotoxicity is a serious health problem that associates the iron overload diseases such
as thalassemia and sickle cell anemia. Induction of oxidative tissue injury and inflammation …

Cognitive decline in dementia is associated with deficiency of the cholinergic system. In this
study, five mono-carbonyl curcumin analogs were synthesized, and on the basis of their …

Aims The current study explored the anti-nociceptive activity of magnolol in post-incisional
inflammatory nociceptive pain. Main methods Preliminary, the anti-inflammatory, antioxidant …

Cystitis is a chronic bladder pain associated with frequency and nocturia. In the present
study, Icariin a prenylated flavonoid extracted from Epimedium koreanum, was investigated …

Ulcerative colitis (UC) is a type of inflammatory bowel disease characterized by
inflammation, ulcers and irritation of the mucosal lining. Oral drug delivery in UC encounters …