Epigallocatechin-3-gallate: A phytochemical as a promising drug candidate for the treatment of Parkinson's disease
Epigallocatechin 3-gallate (EGCG), an abundant polyphenolic component derived from
green tea extract, possesses versatile bioactivities that can combat many diseases. During …
green tea extract, possesses versatile bioactivities that can combat many diseases. During …
Microglia and astrocytes dysfunction and key neuroinflammation-based biomarkers in Parkinson's disease
K Chen, H Wang, I Ilyas, A Mahmood, L Hou - Brain Sciences, 2023 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disease, with
symptoms such as tremor, bradykinesia with rigidity, and depression appearing in the late …
symptoms such as tremor, bradykinesia with rigidity, and depression appearing in the late …
Lactobacillus plantarum CCFM405 against Rotenone-Induced Parkinson's Disease Mice via Regulating Gut Microbiota and Branched-Chain Amino Acids …
Recent studies have demonstrated that disturbances in the gut microbiota and microbiota-
derived metabolites contribute to the pathogenesis of Parkinson's disease (PD), suggesting …
derived metabolites contribute to the pathogenesis of Parkinson's disease (PD), suggesting …
[HTML][HTML] Correlation between the gut microbiome and neurodegenerative diseases: a review of metagenomics evidence
X Liu, Y Liu, J Liu, H Zhang, C Shan… - Neural Regeneration …, 2024 - journals.lww.com
A growing body of evidence suggests that the gut microbiota contributes to the development
of neurodegenerative diseases via the microbiota-gut-brain axis. As a contributing factor …
of neurodegenerative diseases via the microbiota-gut-brain axis. As a contributing factor …
Lewy bodies, iron, inflammation and neuromelanin: pathological aspects underlying Parkinson's disease
Since the description of some peculiar symptoms by James Parkinson in 1817, attempts
have been made to define its cause or at least to enlighten the pathology of “Parkinson's …
have been made to define its cause or at least to enlighten the pathology of “Parkinson's …
[HTML][HTML] Lipopolysaccharide-induced animal models for neuroinflammation–An overview.
AAF da Silva, MB Fiadeiro, LI Bernardino… - Journal of …, 2024 - Elsevier
Neuroinflammation is a pathological mechanism contributing to neurodegenerative
diseases. For in-depth studies of neuroinflammation, several animal models reported …
diseases. For in-depth studies of neuroinflammation, several animal models reported …
Neuroinflammation and mitochondrial dysfunction in parkinson's disease: connecting neuroimaging with pathophysiology
There is a pressing need for disease-modifying therapies in patients suffering from
neurodegenerative diseases, including Parkinson's disease (PD). However, these disorders …
neurodegenerative diseases, including Parkinson's disease (PD). However, these disorders …
QEEG indices are associated with inflammatory and metabolic risk factors in Parkinson's disease dementia: an observational study
H Liu, B Deng, H Zhou, Z Wu, Y Chen, G Weng… - …, 2022 - thelancet.com
Background Quantitative electroencephalography (QEEG) is a reliable and non-invasive
diagnostic tool to quantify cortical synaptic injury or loss in the clinical assessment of …
diagnostic tool to quantify cortical synaptic injury or loss in the clinical assessment of …
[HTML][HTML] Exploring fecal microbiota transplantation for modulating inflammation in parkinson's disease: A review of inflammatory markers and potential effects
K Sadowski, W Zając, Ł Milanowski… - International Journal of …, 2024 - mdpi.com
Parkinson's disease (PD) is a complex neurodegenerative disorder characterized by
numerous motor and non-motor symptoms. Recent data highlight a potential interplay …
numerous motor and non-motor symptoms. Recent data highlight a potential interplay …
Inflammatory blood biomarkers are associated with long-term clinical disease severity in Parkinson's disease
DH Hepp, TA van Wageningen, KL Kuiper… - International journal of …, 2023 - mdpi.com
An altered immune response has been identified as a pathophysiological factor in
Parkinson's disease (PD). We aimed to identify blood immunity-associated proteins that …
Parkinson's disease (PD). We aimed to identify blood immunity-associated proteins that …