Fascia is a cacophony of functions and information, a completely adaptable entropy
complex. The fascial system has a solid and a liquid component, acting in a perfect …

Mechanical forces play an important role in various physiological processes, such as
morphogenesis, cytokinesis, and migration. Thus, in order to illuminate mechanisms …

Over the past few decades, microrheology has emerged as a widely used technique to
measure the mechanical properties of soft viscoelastic materials. Optical tweezers offer a …

Cells constantly encounter mechanical forces that regulate various cellular functions, such
as migration, division, and differentiation. Understanding how cells respond to forces at the …

The cytoskeleton is a major determinant of cell mechanics, and alterations in the central
mechanical aspects of cells are observed during many pathological situations. Therefore, it …

We investigate the fluctuating dynamics of colloidal particles in weakly crosslinked F-actin
networks with optical-trap-based microrheology. Using the dual-feedback technology …

The intrinsic genetic program of a cell is not sufficient to explain all of the cell's activities.
External mechanical stimuli are increasingly recognized as determinants of cell behavior. In …

The cytoskeleton precisely tunes its mechanics by altering interactions between semiflexible
actin filaments, rigid microtubules, and crosslinking proteins. We use optical tweezers …

The cytoskeleton, a complex network of protein filaments and crosslinking proteins, dictates
diverse cellular processes ranging from division to cargo transport. Yet, the role the …

The cytoskeleton is able to precisely tune its structure and mechanics through interactions
between semiflexible actin filaments, rigid microtubules and a suite of crosslinker proteins …