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Mechanisms of cigarette smoke-induced COPD: insights from animal models
A Churg, M Cosio, JL Wright - American Journal of …, 2008 - journals.physiology.org
Cigarette smoke-induced animal models of chronic obstructive pulmonary disease support
the protease-antiprotease hypothesis of emphysema, although which cells and proteases …
the protease-antiprotease hypothesis of emphysema, although which cells and proteases …
Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia
S McGrath-Morrow, T Lauer, M Yee… - … of Physiology-Lung …, 2009 - journals.physiology.org
Increased oxidative stress is associated with perinatal asphyxia and respiratory distress in
the newborn period. Induction of nuclear factor erythroid 2 p45-related factor (Nrf2) has been …
the newborn period. Induction of nuclear factor erythroid 2 p45-related factor (Nrf2) has been …
Impact of acute exposure to cigarette smoke on airway gene expression
E Billatos, A Faiz, Y Gesthalter… - Physiological …, 2018 - journals.physiology.org
Background: Understanding effects of acute smoke exposure (ASE) on airway epithelial
gene expression and their relationship with the effects of chronic smoke exposure may …
gene expression and their relationship with the effects of chronic smoke exposure may …
Gene expression endpoints following chronic waterborne copper exposure in a genomic model organism, the zebrafish, Danio rerio
Although copper (Cu) is an essential micronutrient for all organisms, in excess, waterborne
Cu poses a significant threat to fish from the cellular to population level. We examined the …
Cu poses a significant threat to fish from the cellular to population level. We examined the …
Cigarette smoke preparations, not electronic nicotine delivery system preparations, induce features of lung disease in a 3D lung repeat-dose model
Cigarette smoking is a risk factor for several lung diseases, including chronic obstructive
pulmonary disease, cardiovascular disease, and lung cancer. The potential health effects of …
pulmonary disease, cardiovascular disease, and lung cancer. The potential health effects of …
Basal levels of glutathione peroxidase correlate with onset of radiation induced lung disease in inbred mouse strains
A Kunwar, CK Haston - American Journal of Physiology …, 2014 - journals.physiology.org
Biomarkers predicting for the radiation-induced lung responses of pneumonitis or fibrosis
are largely unknown. Herein we investigated whether markers of oxidative stress and …
are largely unknown. Herein we investigated whether markers of oxidative stress and …
Early response of gene clusters is associated with mouse lung resistance or sensitivity to cigarette smoke
E Cavarra, P Fardin, S Fineschi… - … of Physiology-Lung …, 2009 - journals.physiology.org
We have investigated the effects of cigarette smoke exposure in three different strains of
mice. DBA/2 and C57BL/6J are susceptible to smoke and develop different lung changes in …
mice. DBA/2 and C57BL/6J are susceptible to smoke and develop different lung changes in …
Cigarette smoke preparations, not electronic nicotine delivery systems (ENDS) preparations, induce features of lung disease in a 3D lung repeat-dose model
RE Rayner, P Makena, GL Prasad… - AJP-Lung Cell Mol …, 2020 - journals.physiology.org
Cigarette Smoke Preparations, Not Electronic Nicotine Delivery Systems (ENDS) Preparations,
Induce Features of Lung Disease in a Page 1 Page 1 of 25 Cigarette Smoke Preparations, Not …
Induce Features of Lung Disease in a Page 1 Page 1 of 25 Cigarette Smoke Preparations, Not …
The Impact of Acute Exposure to Cigarette Smoke on Airway Gene Expression 2
IH Hacken, W Timens, CA Brandsma, DS Postma… - journals.physiology.org
111 Results: We identified 91 genes differentially expressed 24-hours after ASE (FDR<
0.25). 112 ASE induced genes involved in xenobiotic metabolism, oxidative stress, and 113 …
0.25). 112 ASE induced genes involved in xenobiotic metabolism, oxidative stress, and 113 …