Integrins are cell adhesion and signalling proteins crucial to a wide range of biological
functions. Effective marketed treatments have successfully targeted integrins αIIbβ3 …

Alcohol use and metabolic syndrome are highly prevalent in the population and frequently
co-exist. Both are implicated in a large range of health problems, including chronic liver …

Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

Cirrhosis, highly prevalent worldwide, develops after years of hepatic inflammation
triggering progressive fibrosis. Currently, the main etiologies of cirrhosis are non‐alcoholic …

NAFLD has become a major public health problem for more than 2 decades with a growing
prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D). The disease …

Cigarette smoking is a preventable risk factor for premature morbidity and mortality. A history
of smoking is observed in approximately 40% of patients with liver disease, while a growing …

Background Non-alcoholic fatty liver disease (NAFLD) is increasingly common in the adult
population. In the United States, the overall burden of NAFLD is unknown due to challenges …

Background and Aims Studies evaluating the association of 2018 Physical Activity
Guidelines for Americans (PA Guidelines) with nonalcoholic fatty liver disease (NAFLD) and …

The ongoing obesity epidemic and the increasing recognition of metabolic syndrome have
contributed to the growing prevalence of nonalcoholic fatty liver disease (NAFLD), the most …

NAFLD/NASH is a sex‐dimorphic disease, with a general higher prevalence in men. Women
are at reduced risk of NAFLD compared to men in fertile age, whereas after menopause …