The Notch signalling pathway is a highly conserved developmental signalling pathway, with
vital roles in determining cell fate during embryonic development and tissue homeostasis …

Germline BRCA1 mutation carriers face a high breast cancer risk; however, the underlying
mechanisms for this risk are not completely understood. Using a new genetically engineered …

Human papillomaviruses (HPV) are a major cause of malignancy worldwide, contributing
to~ 5% of all human cancers including almost all cases of cervical cancer and a growing …

Abstract Triple Negative Breast Cancer (TNBC) is the most aggressive breast cancer
subtype suffering from limited targeted treatment options. Following recent reports …

Background Patients with triple negative breast cancer (TNBC) exhibit poor prognosis and
are at high risk of tumour relapse, due to the resistance to chemotherapy. These aggressive …