Prompt-gamma monitoring in hadrontherapy: A review

J Krimmer, D Dauvergne, JM Létang, É Testa - Nuclear Instruments and …, 2018 - Elsevier
Secondary radiation emission induced by nuclear reactions is correlated to the path of ions
in matter. Therefore, such penetrating radiation can be used for in vivo control of …

Compton imaging for medical applications

H Tashima, T Yamaya - Radiological Physics and Technology, 2022 - Springer
Compton imaging exploits inelastic scattering, known as Compton scattering, using a
Compton camera consisting of a scatterer detector in the front layer and an absorber …

A full-scale clinical prototype for proton range verification using prompt gamma-ray spectroscopy

F Hueso-González, M Rabe, TA Ruggieri… - Physics in Medicine …, 2018 - iopscience.iop.org
We present a full-scale clinical prototype system for in vivo range verification of proton pencil-
beams using the prompt gamma-ray spectroscopy method. The detection system consists of …

3D prompt gamma imaging for proton beam range verification

E Draeger, D Mackin, S Peterson, H Chen… - Physics in Medicine …, 2018 - iopscience.iop.org
We tested the ability of a single Compton camera (CC) to produce 3-dimensional (3D)
images of prompt gammas (PGs) emitted during the irradiation of a tissue-equivalent plastic …

Detection systems for range monitoring in proton therapy: Needs and challenges

G Pausch, J Berthold, W Enghardt, K Römer… - Nuclear Instruments and …, 2020 - Elsevier
In-vivo range verification has been a hot topic in particle therapy for about two decades. In
spite of vast efforts made by research groups all over the world, clinical devices and …

Imaging of 99mTc-DMSA and 18F-FDG in humans using a Si/CdTe Compton camera

T Nakano, M Sakai, K Torikai, Y Suzuki… - Physics in Medicine …, 2020 - iopscience.iop.org
The Compton camera can simultaneously acquire images of multiple isotopes injected in a
body; therefore, it has the potential to introduce a new subfield in the field of biomedical …

Applications of Machine Learning to Improve the Clinical Viability of Compton Camera Based in vivo Range Verification in Proton Radiotherapy

JC Polf, CA Barajas, SW Peterson, DS Mackin… - Frontiers in …, 2022 - frontiersin.org
We studied the application of a deep, fully connected Neural Network (NN) to process
prompt gamma (PG) data measured by a Compton camera (CC) during the delivery of …

Multi-modal 3D imaging of radionuclides using multiple hybrid Compton cameras

A Omata, M Masubuchi, N Koshikawa, J Kataoka… - Scientific reports, 2022 - nature.com
For radiological diagnosis and radionuclide therapy, X-ray and gamma-ray imaging
technologies are essential. Single-photon emission tomography (SPECT) and positron …

Proton range verification with ultrasound imaging using injectable radiation sensitive nanodroplets: a feasibility study

B Carlier, SV Heymans, S Nooijens… - Physics in Medicine …, 2020 - iopscience.iop.org
Technologies enabling in vivo range verification during proton therapy are actively sought
as a means to reduce the clinical safety margins currently adopted to avoid tumor …

CCMod: a GATE module for Compton camera imaging simulation

A Etxebeste, D Dauvergne, M Fontana… - Physics in Medicine …, 2020 - iopscience.iop.org
Compton cameras are gamma-ray imaging systems which have been proposed for a wide
variety of applications such as medical imaging, nuclear decommissioning or homeland …