The role of cigarette smoke-induced pulmonary vascular endothelial cell apoptosis in COPD
Q Song, P Chen, XM Liu - Respiratory Research, 2021 - Springer
Chronic obstructive pulmonary disease (COPD) is one of the most common chronic
respiratory diseases with high morbidity and mortality. It has become the fifth most burdened …
respiratory diseases with high morbidity and mortality. It has become the fifth most burdened …
An epidemiological introduction to human metabolomic investigations
Metabolomics holds great promise for uncovering insights around biological processes
impacting disease in human epidemiological studies. Metabolites can be measured across …
impacting disease in human epidemiological studies. Metabolites can be measured across …
Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation
Dietary fibres can exert beneficial anti-inflammatory effects through microbially fermented
short-chain fatty acid metabolites,, although the immunoregulatory roles of most fibre diets …
short-chain fatty acid metabolites,, although the immunoregulatory roles of most fibre diets …
Lung microbiota and metabolites collectively associate with clinical outcomes in milder stage chronic obstructive pulmonary disease
SS Madapoosi, C Cruickshank-Quinn… - American journal of …, 2022 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is variable in its development.
Lung microbiota and metabolites collectively may impact COPD pathophysiology, but …
Lung microbiota and metabolites collectively may impact COPD pathophysiology, but …
Fecal microbial transplantation and a high fiber diet attenuates emphysema development by suppressing inflammation and apoptosis
Recent work has suggested a microbial dysbiosis association between the lung and gut in
respiratory diseases. Here, we demonstrated that gut microbiome modulation attenuated …
respiratory diseases. Here, we demonstrated that gut microbiome modulation attenuated …
Air pollution, metabolites and respiratory health across the life-course
Previous studies have explored the relationships of air pollution and metabolic profiles with
lung function. However, the metabolites linking air pollution and lung function and the …
lung function. However, the metabolites linking air pollution and lung function and the …
[HTML][HTML] Exploring molecular mechanisms and biomarkers in COPD: an overview of current advancements and perspectives
CL Li, SF Liu - International Journal of Molecular Sciences, 2024 - mdpi.com
Chronic obstructive pulmonary disease (COPD) plays a significant role in global morbidity
and mortality rates, typified by progressive airflow restriction and lingering respiratory …
and mortality rates, typified by progressive airflow restriction and lingering respiratory …
Metabolomic fingerprinting and systemic inflammatory profiling of asthma COPD overlap (ACO)
Abstract Background Asthma-COPD overlap (ACO) refers to a group of poorly studied and
characterised patients reporting with disease presentations of both asthma and COPD …
characterised patients reporting with disease presentations of both asthma and COPD …
Recent evidence from omic analysis for redox signalling and mitochondrial oxidative stress in COPD
COPD is driven by exogenous and endogenous oxidative stress derived from inhaled
cigarette smoke, air pollution and reactive oxygen species from dysregulated mitochondria …
cigarette smoke, air pollution and reactive oxygen species from dysregulated mitochondria …
[HTML][HTML] Metabolic differences between bronchial epithelium from healthy individuals and patients with asthma and the effect of bronchial thermoplasty
A Ravi, AWM Goorsenberg, A Dijkhuis… - Journal of Allergy and …, 2021 - Elsevier
Background Asthma is a heterogeneous disease with differences in onset, severity, and
inflammation. Bronchial epithelial cells (BECs) contribute to asthma pathophysiology …
inflammation. Bronchial epithelial cells (BECs) contribute to asthma pathophysiology …