Light sheet fluorescence microscopy

EHK Stelzer, F Strobl, BJ Chang, F Preusser… - Nature Reviews …, 2021 - nature.com
Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

AI on a chip

A Isozaki, J Harmon, Y Zhou, S Li, Y Nakagawa… - Lab on a Chip, 2020 - pubs.rsc.org
Artificial intelligence (AI) has dramatically changed the landscape of science, industry,
defence, and medicine in the last several years. Supported by considerably enhanced …

Stain-free identification of cell nuclei using tomographic phase microscopy in flow cytometry

D Pirone, J Lim, F Merola, L Miccio, M Mugnano… - Nature …, 2022 - nature.com
Quantitative phase imaging has gained popularity in bioimaging because it can avoid the
need for cell staining, which, in some cases, is difficult or impossible. However, as a result …

Light-field flow cytometry for high-resolution, volumetric and multiparametric 3D single-cell analysis

X Hua, K Han, B Mandracchia, A Radmand… - Nature …, 2024 - nature.com
Imaging flow cytometry (IFC) combines flow cytometry and fluorescence microscopy to
enable high-throughput, multiparametric single-cell analysis with rich spatial details …

Neuromorphic-enabled video-activated cell sorting

W He, J Zhu, Y Feng, F Liang, K You, H Chai… - Nature …, 2024 - nature.com
Imaging flow cytometry allows image-activated cell sorting (IACS) with enhanced feature
dimensions in cellular morphology, structure, and composition. However, existing IACS …

Tomographic imaging flow cytometry

A Kleiber, D Kraus, T Henkel, W Fritzsche - Lab on a Chip, 2021 - pubs.rsc.org
Within the last decades, conventional flow cytometry (FC) has evolved as a powerful
measurement method in clinical diagnostics, biology, life sciences and healthcare. Imaging …

Microfluidic based optical microscopes on chip

P Paiè, R Martínez Vázquez, R Osellame… - Cytometry Part …, 2018 - Wiley Online Library
Last decade's advancements in optofluidics allowed obtaining an ever increasing
integration of different functionalities in lab on chip devices to culture, analyze, and …

Detection of rare objects by flow cytometry: imaging, cell sorting, and deep learning approaches

DV Voronin, AA Kozlova, RA Verkhovskii… - International journal of …, 2020 - mdpi.com
Flow cytometry nowadays is among the main working instruments in modern biology paving
the way for clinics to provide early, quick, and reliable diagnostics of many blood-related …

High-throughput 3D imaging of single cells with light-sheet fluorescence microscopy on chip

F Sala, M Castriotta, P Paiè, A Farina… - Biomedical optics …, 2020 - opg.optica.org
Single-cell analysis techniques are fundamental to study the heterogeneity of cellular
populations, which is the basis to understand several biomedical mechanisms. Light-sheet …

[HTML][HTML] End-fire silicon optical phased array with half-wavelength spacing

MR Kossey, C Rizk, AC Foster - APL Photonics, 2018 - pubs.aip.org
A multitude of applications depend on the ability to quickly and accurately steer a laser
beam, ranging from fiber endoscopes in biological imaging to light detection and ranging …