Bioengineered nanogels for cancer immunotherapy

X Ma, SJ Li, Y Liu, T Zhang, P Xue, Y Kang… - Chemical Society …, 2022 - pubs.rsc.org
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Responsive biomaterials: optimizing control of cancer immunotherapy

L Xue, AS Thatte, D Mai, RM Haley, N Gong… - Nature Reviews …, 2024 - nature.com
Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …

Semiconducting polymer nanoparticles with surface‐mimicking protein secondary structure as lysosome‐targeting chimaeras for self‐synergistic cancer …

J Qi, S Jia, X Kang, X Wu, Y Hong, K Shan… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has received tremendous attention for tumor treatment, but the efficacy is
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …

Biomaterials for in situ cell therapy

C Wang, S Wang, DD Kang, Y Dong - BMEMat, 2023 - Wiley Online Library
Cell therapy has revolutionized the treatment of various diseases, such as cancers, genetic
disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo …

Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine

X Wang, P Hua, C He, M Chen - Acta Pharmaceutica Sinica B, 2022 - Elsevier
As an emerging cancer therapeutic target, non-apoptotic cell death such as ferroptosis,
necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for …

3-Bromopyruvate-conjugated nanoplatform-induced pro-death autophagy for enhanced photodynamic therapy against hypoxic tumor

Y Deng, P Song, X Chen, Y Huang, L Hong, Q **… - ACS nano, 2020 - ACS Publications
Autophagy triggered by reactive oxygen species (ROS) in photodynamic therapy (PDT)
generally exhibits an anti-apoptotic effect to promote cell survival. Herein, an innovative …

Enhanced Immunogenic Cell Death and Antigen Presentation via Engineered Bifidobacterium bifidum to Boost Chemo-immunotherapy

T He, L Wang, S Gou, L Lu, G Liu, K Wang, Y Yang… - ACS …, 2023 - ACS Publications
The immunogenic cell death (ICD) of tumor cells has aroused great interest in the field of
immunotherapy, mainly due to the production of plentiful tumor-associated antigens (TAAs) …

Autophagy-targeted nanoparticles for effective cancer treatment: advances and outlook

X Long, J Yan, Z Zhang, J Chang, B He, Y Sun… - NPG Asia …, 2022 - nature.com
Autophagy enables the maintenance of nutrient recycling and metabolic homeostasis
through a multistep lysosomal degradation pathway, and it has been demonstrated that …

Supramolecular biomaterials for cancer immunotherapy

H Liang, Q Lu, J Yang, G Yu - Research, 2023 - spj.science.org
Cancer immunotherapy has achieved tremendous successful clinical results and obtained
historic victories in tumor treatments. However, great limitations associated with feeble …

Role of autophagy on cancer immune escape

Y Duan, X Tian, Q Liu, J **, J Shi, Y Hou - Cell Communication and …, 2021 - Springer
Autophagy is catabolic process by degradation of intracellular components in lysosome
including proteins, lipids, and mitochondria in response to nutrient deficiency or stress such …