Bioengineered nanogels for cancer immunotherapy
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
Responsive biomaterials: optimizing control of cancer immunotherapy
Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …
cancer. However, current cancer immunotherapies lack spatial and temporal control …
Semiconducting polymer nanoparticles with surface‐mimicking protein secondary structure as lysosome‐targeting chimaeras for self‐synergistic cancer …
Immunotherapy has received tremendous attention for tumor treatment, but the efficacy is
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …
Biomaterials for in situ cell therapy
Cell therapy has revolutionized the treatment of various diseases, such as cancers, genetic
disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo …
disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo …
Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine
As an emerging cancer therapeutic target, non-apoptotic cell death such as ferroptosis,
necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for …
necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for …
3-Bromopyruvate-conjugated nanoplatform-induced pro-death autophagy for enhanced photodynamic therapy against hypoxic tumor
Y Deng, P Song, X Chen, Y Huang, L Hong, Q **… - ACS nano, 2020 - ACS Publications
Autophagy triggered by reactive oxygen species (ROS) in photodynamic therapy (PDT)
generally exhibits an anti-apoptotic effect to promote cell survival. Herein, an innovative …
generally exhibits an anti-apoptotic effect to promote cell survival. Herein, an innovative …
Enhanced Immunogenic Cell Death and Antigen Presentation via Engineered Bifidobacterium bifidum to Boost Chemo-immunotherapy
T He, L Wang, S Gou, L Lu, G Liu, K Wang, Y Yang… - ACS …, 2023 - ACS Publications
The immunogenic cell death (ICD) of tumor cells has aroused great interest in the field of
immunotherapy, mainly due to the production of plentiful tumor-associated antigens (TAAs) …
immunotherapy, mainly due to the production of plentiful tumor-associated antigens (TAAs) …
Autophagy-targeted nanoparticles for effective cancer treatment: advances and outlook
X Long, J Yan, Z Zhang, J Chang, B He, Y Sun… - NPG Asia …, 2022 - nature.com
Autophagy enables the maintenance of nutrient recycling and metabolic homeostasis
through a multistep lysosomal degradation pathway, and it has been demonstrated that …
through a multistep lysosomal degradation pathway, and it has been demonstrated that …
Supramolecular biomaterials for cancer immunotherapy
H Liang, Q Lu, J Yang, G Yu - Research, 2023 - spj.science.org
Cancer immunotherapy has achieved tremendous successful clinical results and obtained
historic victories in tumor treatments. However, great limitations associated with feeble …
historic victories in tumor treatments. However, great limitations associated with feeble …
Role of autophagy on cancer immune escape
Y Duan, X Tian, Q Liu, J **, J Shi, Y Hou - Cell Communication and …, 2021 - Springer
Autophagy is catabolic process by degradation of intracellular components in lysosome
including proteins, lipids, and mitochondria in response to nutrient deficiency or stress such …
including proteins, lipids, and mitochondria in response to nutrient deficiency or stress such …