One Ring to Bind Them All”—Part I: The Efficiency of the Macrocyclic Scaffold for G‐Quadruplex DNA Recognition

D Monchaud, A Granzhan, N Saettel… - Journal of Nucleic …, 2010 - Wiley Online Library
Macrocyclic scaffolds are particularly attractive for designing selective G‐quadruplex ligands
essentially because, on one hand, they show a poor affinity for the “standard” B‐DNA …

Selective photodynamic therapy based on aggregation-induced emission enhancement of fluorescent organic nanoparticles

CC Chang, MC Hsieh, JC Lin, TC Chang - Biomaterials, 2012 - Elsevier
Three binary molecule conjugates were designed and synthesized by conjugating a
chromophore (3, 6-bis-(1-methyl-4-vinylpyridinium)-carbazole diiodide, BMVC) to mono-, bis …

Optimizing the antitumor selectivity of PVP-Hypericin re A549 cancer cells and HLF normal cells through pulsed blue light

R Penjweini, HG Loew, P Breit, KW Kratky - … and photodynamic therapy, 2013 - Elsevier
Photodynamic therapy (PDT) is based on the preferential accumulation of photosensitizer in
cancer cells with subsequent cytotoxicity mediated by singlet oxygen production after light …

Aggregation induced photodynamic therapy enhancement based on linear and nonlinear excited FRET of fluorescent organic nanoparticles

MC Hsieh, CH Chien, CC Chang… - Journal of Materials …, 2013 - pubs.rsc.org
A binary molecule can self-assemble to form fluorescent organic nanoparticles (FONs)
based on the Aggregation-Induced Emission Enhancement (AIEE) property and …

[HTML][HTML] Shedding lights on the flexible-armed porphyrins: human telomeric G4 DNA interaction and cell photocytotoxicity research

XY Sun, P Zhao, S **, MC Liu, X Wang… - … of Photochemistry and …, 2017 - Elsevier
DNA polymorphism exerts a fascination on a large scientific community. Without
crystallographic structural data, clarification of the binding modes between G-quadruplex …

Imaging Study of Small Molecules to G-Quadruplexes in Cells

TY Tseng, TC Chang - Handbook of Chemical Biology of Nucleic Acids, 2023 - Springer
Many guanine-rich oligonucleotides are found in the human genome, which may fold into G-
quadruplex (G4) structures under physiological conditions. Accumulating evidence suggests …

Bifunctional agents for imaging and therapy

RK Pandey, NS James, Y Chen, J Missert… - … Therapy: Methods and …, 2010 - Springer
Multiple, complementary techniques for tumor detection, including magnetic resonance,
nuclear and optical imaging, are under active development; each approach has particular …

Acri‐2, 7‐Py, a bright red‐emitting DNA probe identified through screening of a distyryl dye library

D Naud‐Martin, X Martin‐Benlloch, F Poyer… - Biotechnology …, 2014 - Wiley Online Library
The identification of DNA sensors is still a challenge since no DNA probe possesses all the
photophysical properties required for live‐cell imaging: high fluorescence yield, red …

Sondes fluorescentes vinyl-triphénylamines optimisées pour la microscopie biphotonique: Etude des intéractions non covalentes avec l'ADN et la HSA et application à …

B Dumat - 2012 - theses.hal.science
L'avènement de la microscopie biphotonique et des techniques dites de «super-résolution»
ont permis d'améliorer les performances de la microscopie de fluorescence et de l'appliquer …

[PDF][PDF] Nanoparticules multifonctionnelles excitables par les rayons X pour la thérapie photodynamique

R Chouikrat - Laboratoire Reactions et Genie des Procedes, 2015 - docnum.univ-lorraine.fr
Over the last few years, photodynamic therapy (PDT) has emerged as an alternative to
chemotherapy and radiotherapy for the treatment ofvarious dise ases including cancer [1, 2] …