“One Ring to Bind Them All”—Part I: The Efficiency of the Macrocyclic Scaffold for G‐Quadruplex DNA Recognition
Macrocyclic scaffolds are particularly attractive for designing selective G‐quadruplex ligands
essentially because, on one hand, they show a poor affinity for the “standard” B‐DNA …
essentially because, on one hand, they show a poor affinity for the “standard” B‐DNA …
Selective photodynamic therapy based on aggregation-induced emission enhancement of fluorescent organic nanoparticles
CC Chang, MC Hsieh, JC Lin, TC Chang - Biomaterials, 2012 - Elsevier
Three binary molecule conjugates were designed and synthesized by conjugating a
chromophore (3, 6-bis-(1-methyl-4-vinylpyridinium)-carbazole diiodide, BMVC) to mono-, bis …
chromophore (3, 6-bis-(1-methyl-4-vinylpyridinium)-carbazole diiodide, BMVC) to mono-, bis …
Optimizing the antitumor selectivity of PVP-Hypericin re A549 cancer cells and HLF normal cells through pulsed blue light
Photodynamic therapy (PDT) is based on the preferential accumulation of photosensitizer in
cancer cells with subsequent cytotoxicity mediated by singlet oxygen production after light …
cancer cells with subsequent cytotoxicity mediated by singlet oxygen production after light …
Aggregation induced photodynamic therapy enhancement based on linear and nonlinear excited FRET of fluorescent organic nanoparticles
MC Hsieh, CH Chien, CC Chang… - Journal of Materials …, 2013 - pubs.rsc.org
A binary molecule can self-assemble to form fluorescent organic nanoparticles (FONs)
based on the Aggregation-Induced Emission Enhancement (AIEE) property and …
based on the Aggregation-Induced Emission Enhancement (AIEE) property and …
[HTML][HTML] Shedding lights on the flexible-armed porphyrins: human telomeric G4 DNA interaction and cell photocytotoxicity research
XY Sun, P Zhao, S **, MC Liu, X Wang… - … of Photochemistry and …, 2017 - Elsevier
DNA polymorphism exerts a fascination on a large scientific community. Without
crystallographic structural data, clarification of the binding modes between G-quadruplex …
crystallographic structural data, clarification of the binding modes between G-quadruplex …
Imaging Study of Small Molecules to G-Quadruplexes in Cells
TY Tseng, TC Chang - Handbook of Chemical Biology of Nucleic Acids, 2023 - Springer
Many guanine-rich oligonucleotides are found in the human genome, which may fold into G-
quadruplex (G4) structures under physiological conditions. Accumulating evidence suggests …
quadruplex (G4) structures under physiological conditions. Accumulating evidence suggests …
Bifunctional agents for imaging and therapy
RK Pandey, NS James, Y Chen, J Missert… - … Therapy: Methods and …, 2010 - Springer
Multiple, complementary techniques for tumor detection, including magnetic resonance,
nuclear and optical imaging, are under active development; each approach has particular …
nuclear and optical imaging, are under active development; each approach has particular …
Acri‐2, 7‐Py, a bright red‐emitting DNA probe identified through screening of a distyryl dye library
D Naud‐Martin, X Martin‐Benlloch, F Poyer… - Biotechnology …, 2014 - Wiley Online Library
The identification of DNA sensors is still a challenge since no DNA probe possesses all the
photophysical properties required for live‐cell imaging: high fluorescence yield, red …
photophysical properties required for live‐cell imaging: high fluorescence yield, red …
Sondes fluorescentes vinyl-triphénylamines optimisées pour la microscopie biphotonique: Etude des intéractions non covalentes avec l'ADN et la HSA et application à …
B Dumat - 2012 - theses.hal.science
L'avènement de la microscopie biphotonique et des techniques dites de «super-résolution»
ont permis d'améliorer les performances de la microscopie de fluorescence et de l'appliquer …
ont permis d'améliorer les performances de la microscopie de fluorescence et de l'appliquer …
[PDF][PDF] Nanoparticules multifonctionnelles excitables par les rayons X pour la thérapie photodynamique
R Chouikrat - Laboratoire Reactions et Genie des Procedes, 2015 - docnum.univ-lorraine.fr
Over the last few years, photodynamic therapy (PDT) has emerged as an alternative to
chemotherapy and radiotherapy for the treatment ofvarious dise ases including cancer [1, 2] …
chemotherapy and radiotherapy for the treatment ofvarious dise ases including cancer [1, 2] …