Quinoxaline as ubiquitous structural fragment: an update on the recent development of its green synthetic approaches
Quinoxaline is a versatile heterocyclic moiety that possesses a wide range of biological
activities. Therefore, many researchers have been performing the synthesis of quinoxaline …
activities. Therefore, many researchers have been performing the synthesis of quinoxaline …
Heterocyclic scaffolds for the treatment of Alzheimer's disease
Background: The treatment and diagnosis of Alzheimer's Disease (AD) are two of the most
urgent goals for research around the world. The cognitive decline is generally associated …
urgent goals for research around the world. The cognitive decline is generally associated …
Quinoxaline nucleus: a promising scaffold in anti-cancer drug discovery
AC Pinheiro, TC Mendonça Nogueira… - Anti-Cancer Agents …, 2016 - ingentaconnect.com
Heterocyclic compounds are a class of substances, which play a critical role in modern drug
discovery being incorporated in the structure of a large variety of drugs used in many …
discovery being incorporated in the structure of a large variety of drugs used in many …
An “all-water” strategy for regiocontrolled synthesis of 2-aryl quinoxalines
A new synthetic strategy of tandem N-aroylmethylation-nitro reduction–cyclocondensation
has been developed for the first and generalized regioselective synthesis of 2-aryl …
has been developed for the first and generalized regioselective synthesis of 2-aryl …
Synthesis and Biological Evaluation of Some N-Substituted Quinoxaline Derivatives as Antitumor Agents
AA Gobouri - Russian Journal of Bioorganic Chemistry, 2020 - Springer
A new hybrid molecules containing 1-(N-substituted)-quinoxaline derivatives were
synthesized from condensation of 3-hydroxy-2-oxo quinoxaline with 2, 3-unsaturated …
synthesized from condensation of 3-hydroxy-2-oxo quinoxaline with 2, 3-unsaturated …
An expedient sequential one-pot four component synthesis of novel steroidal spiro-pyrrolidine heterocycles in ionic liquid
D Gavaskar, ARS Babu, R Raghunathan, M Dharani… - Steroids, 2016 - Elsevier
A facile one-pot synthesis of novel steroidal dispiro-indenoquinoxaline pyrrolidines via
multicomponent-[3+ 2]-cycloaddition of azomethine ylides in ionic liquid is described. The …
multicomponent-[3+ 2]-cycloaddition of azomethine ylides in ionic liquid is described. The …
Synthesis, Docking, and Evaluation of Antimicrobial Activity of a New Series of Acyclo C‐Nucleosides of 1, 2, 4‐Triazolo[4, 3‐a]quinoxaline Derivatives
In this study, 18 new 3‐benzylquinoxalinyl hydrazones bearing carbohydrate moiety and
their corresponding triazoloquinoxalines were synthesized in order to investigate their …
their corresponding triazoloquinoxalines were synthesized in order to investigate their …
Synthesis of quinoxalines using Gum Arabic as a nontoxic metal-free biocatalyst at room temperature in aqueous media
SA Fazeli-Attar, BBF Mirjalili - Environmental Chemistry Letters, 2018 - Springer
In the present study, Gum Arabic was used as a metal-free biocatalyst in the synthesis of
quinoxaline derivatives through condensation of 1, 2-diamines and 1, 2-dicarbonyl …
quinoxaline derivatives through condensation of 1, 2-diamines and 1, 2-dicarbonyl …
Porous catalytic systems in the synthesis of bioactive heterocycles and related compounds
Synthesis of heterocyclic compounds is an important issue in organic chemistry. A large
variety of natural products such as hormones, vitamins, and even antibiotics essential for …
variety of natural products such as hormones, vitamins, and even antibiotics essential for …
Sustainable approaches towards the synthesis of quinoxalines
The quinoxaline (Qx) nucleus is present in various bioactive molecules. Thus, synthesis of
Qxs continues to draw the attention of synthetic organic/medicinal chemists. The …
Qxs continues to draw the attention of synthetic organic/medicinal chemists. The …