Genome-wide association studies that scan the genome for common genetic variants
associated with phenotype have greatly advanced medical knowledge. Hyperuricemia is no …

Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic
health. To date, most genetic studies of glycemic traits have focused on individuals of …

The central feature of gout is deposition of inflammatory monosodium urate (MSU)
monohydrate microcrystals, which can lead to acute inflammatory arthritis, tendonitis …

Renal proximal tubule epithelial cells have considerable intrinsic repair capacity following
injury. However, a fraction of injured proximal tubule cells fails to undergo normal repair and …

Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We
analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for …

Background: Type 2 diabetes mellitus (T2DM) is the most common metabolic disorder. The
aim of the present investigation was to identify gene signature specific to T2DM. Methods …

We performed integrative analysis of genes associated with type 2 Diabetes Mellitus (T2DM)
associated complications by automated text mining with manual curation and also gene …

Frugivory evolved multiple times in mammals, including bats. However, the cellular and
molecular components driving it remain largely unknown. Here, we use integrative single …

Background Cardiovascular disease (CVD) describes the pathological conditions of the
heart and blood vessels. Despite the large number of studies on CVD and its etiology, its key …

Abstract Purpose of Review Diabetic complications affecting the kidneys, retina, nerves, and
the cardiovasculature are the major causes of morbidity and mortality in diabetes. This paper …