Abstract Parkinson's disease (PD), the second most common neurodegenerative disorder,
affects 1–2% of humans aged 60 years and older. The diagnosis of PD is based on motor …

Neurogenesis is the process of forming new neurons from neural stem cells (NSCs). In
adults, this process takes place in specific areas of the brain, known as neurogenic niches …

Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease, and its incidence is predicted to increase worldwide. Striatal dopamine …

Growing evidence has demonstrated that neurogenesis in the subventricular zone (SVZ) is
significantly decreased in Parkinson's disease (PD). Modulation of endogenous …

Restorative/protective therapies to restore dopamine neurons in the substantia nigra pars
compacta (SNpc) are greatly needed to effectively change the debilitating course of …

The primary clinical motor symptoms of Parkinson's disease (PD) result from loss of
dopaminergic (DA) neurons in the substantia nigra (SN). Consequently, neurogenesis of this …

The adult newt brain has a marked neurogenic potential and is highly regenerative.
Ventricular, radial glia-like ependymoglia cells give rise to neurons both during normal …

Endogenous neural stem cells are thought to continue to generate new neurons throughout
life in the human brain. Endogenous neurogenesis has been proposed to contribute to …

Parkinson's Disease (PD) is a brain-degenerative disorder characterized by a progressive
loss of midbrain dopamine neurons. Current standard-of-care includes oral administration of …

More than a third of Alzheimer's disease (AD) patients show nigrostriatal pathway
disturbances, resulting in akinesia (inability to initiate movement) and bradykinesia …