In vitro cytotoxic activity of african plants: A review

I Canga, P Vita, AI Oliveira, MÁ Castro, C Pinho - Molecules, 2022 - mdpi.com
In African countries, cancer not only is a growing problem, but also a challenge because
available funding and resources are limited. Therefore, African medicinal plants play a …

Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines

LM Youmbi, YSD Makong, AT Mbaveng… - … Medicine and Therapies, 2023 - Springer
Background Cancer remains a global health concern and constitutes an important barrier to
increasing life expectancy. Malignant cells rapidly develop drug resistance leading to many …

A brief study on drug repurposing: new way of boosting drug discovery

KK Kaushik, R Mazumder, A Debnath… - Letters in Drug Design …, 2023 - benthamdirect.com
Background: Even with the massive increase in financial investments in pharmaceutical
research over the last decade, the number of new drugs approved has plummeted. As a …

Evaluation of Annona muricata extract against Staphylococcus aureus isolate and in-silico activity of bioactive compounds against Capsular protein (Cap5O)

UO Edet, FO Nwaokorie, EN Mbim, EE Asanga… - … Medicine and Therapies, 2022 - Springer
Background Staphylococcus aureus has prevailed against the majority of antibiotics
currently in clinical use, making it a significant global public health problem. As a safer …

Ethnopharmacology, phytochemistry and pharmacology of potent antibacterial medicinal plants from Africa

V Kuete - Advances in Botanical Research, 2023 - Elsevier
In this chapter, the traditional use, the phytochemical composition, and the pharmacological
activities of African medicinal plants displaying antibacterial effects were reported. We have …

Prenylated Flavonoids and C-15 Isoprenoid Analogues with Antibacterial Properties from the Whole Plant of Imperata cylindrica (L.) Raeusch (Gramineae)

RDT Nago, P Nayim, AT Mbaveng, JDS Mpetga… - Molecules, 2021 - mdpi.com
The local botanical Imperata cylindrica in Cameroon was investigated for its antibacterial
potency. The methanol extract afforded a total of seven compounds, including five hitherto …

Potential of African flora to combat tuberculosis and drug resistance of Mycobacteria: Rationale classification of antimycobacterial agents from a natural source

CF Tchinda, V Kuete - Advances in Botanical Research, 2023 - Elsevier
This chapter presents a synopsis of African medicinal plants and their derived products with
antimycobacterial properties. Several secondary plant metabolites are reported to have anti …

[HTML][HTML] Optimized ultrasound-assisted recovery, HPLC/LC-MS identification and biological activities of Tetrapleura tetraptera L. dry fruit polyphenols

CS Dzah - Food Chemistry Advances, 2022 - Elsevier
Little information exists in literature about the optimization of ultrasound-assisted extraction
(UAE) of Tetrapleura tetraptera (TT) fruit polyphenols (TTP). The use of conventional …

Potential antibacterial pharmaceuticals from the flora of Africa

AT Mbaveng, LK Omosa, GTM Bitchagno… - Advances in Botanical …, 2023 - Elsevier
The present chapter highlights the antibacterial potential of nine highly active compounds
isolated from the African medicinal plants: 8, 8-bis-(dihydroconiferyl)-diferulate, buesgenine …

Cytotoxicity, acute and sub-chronic toxicities of the fruit extract of Tetrapleura tetraptera (Schumm. & Thonn.) Taub. (Fabaceae)

IN Bonsou, AT Mbaveng, GS Nguenang, GF Chi… - … medicine and therapies, 2022 - Springer
Background Tetrapleura tetraptera is a medicinal spice traditionally used to treat cancer,
diabetes, and several other ailments. This study analyzed the cytotoxicity of the …