Information on the penetration depth, pathways, metabolization, storage of vehicles, active
pharmaceutical ingredients (APIs), and functional cosmetic ingredients (FCIs) of topically …

The skin is the largest organ in humans. It comprises about 16% of our body. Many diseases
originate from the skin, including acne vulgaris, skin cancer, fungal skin disease, etc. As a …

Hyaluronic acid (HA) has been widely used in cosmetics and topical preparations owing to
its favorable moisturizing property and potential in enhancing drugs' skin permeability. Here …

α-Aminophosphonates are organophosphorus compounds with an obvious similarity with α-
amino acids. Owing to their biological and pharmacological characteristics, they have …

Based on our previous report, the study was extended to investigate the impact of
miconazole nitrate (MCN) loaded cationic/anionic nanoemulsions and nanoemulsion gels …

The quantitative determination of topically applied substances in the skin is severely limited
and represents a challenging task. The porcine skin ex vivo was topically treated with a gel …

Acyclovir (ACV) controls cutaneous herpes, genital herpes, herpes keratitis, varicella zoster,
and chickenpox. From previously reported ACV formulations, we continued to explore the …

Skin is the largest organ and a multifunctional interface between the body and its
environment. It acts as a barrier against cold, heat, injuries, infections, chemicals, radiations …

In recent days, the utilization of the skin as a pathway for drug delivery has gained
substantial popularity and recognition. The skin's natural barrier properties pose a significant …

Abstract The FDA Modernization Act 2.0 has brought nonclinical drug evaluation into a new
era. In vitro models are widely used and play an important role in modern drug development …