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Multisystem physiological perspective of human frailty and its modulation by physical activity
“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …
Instruments for the detection of frailty syndrome in older adults: a systematic review
Frailty is a dynamic process in which there is a reduction in the physical, psychological
and/or social function associated with aging. The aim of this study was to identify instruments …
and/or social function associated with aging. The aim of this study was to identify instruments …
[HTML][HTML] Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 UK Biobank …
Background Frailty is associated with older age and multimorbidity (two or more long-term
conditions); however, little is known about its prevalence or effects on mortality in younger …
conditions); however, little is known about its prevalence or effects on mortality in younger …
Frailty and the prediction of negative health outcomes: a meta-analysis
S Vermeiren, R Vella-Azzopardi, D Beckwee… - Journal of the American …, 2016 - Elsevier
Introduction Frailty is one of the most important concerns regarding our aging population.
Evidence grows that the syndrome is linked to several important health outcomes. A general …
Evidence grows that the syndrome is linked to several important health outcomes. A general …
[HTML][HTML] Frailty and sarcopenia: the potential role of an aged immune system
Frailty is a common negative consequence of ageing. Sarcopenia, the syndrome of loss of
muscle mass, quality and strength, is more common in older adults and has been …
muscle mass, quality and strength, is more common in older adults and has been …
Frailty assessment instruments: systematic characterization of the uses and contexts of highly-cited instruments
The medical syndrome of frailty is widely recognized, yet debate remains over how best to
measure it in clinical and research settings. This study reviewed the frailty-related research …
measure it in clinical and research settings. This study reviewed the frailty-related research …
Effectiveness of exercise interventions on physical function in community-dwelling frail older people: an umbrella review of systematic reviews
AD Jadczak, N Makwana… - JBI Evidence …, 2018 - journals.lww.com
Objectives: This umbrella review aimed to determine the effectiveness of exercise
interventions, alone or in combination with other interventions, in improving physical function …
interventions, alone or in combination with other interventions, in improving physical function …
Differences in handgrip strength protocols to identify sarcopenia and frailty-a systematic review
Background Hand grip strength (HGS) is used for the diagnosis of sarcopenia and frailty.
Several factors have been shown to influence HGS values during measurement. Therefore …
Several factors have been shown to influence HGS values during measurement. Therefore …
Agreement between 35 published frailty scores in the general population
In elderly populations, frailty is associated with higher mortality risk. Although many frailty
scores (FS) have been proposed, no single score is considered the gold standard. We …
scores (FS) have been proposed, no single score is considered the gold standard. We …
Effects of multi-domain interventions in (pre) frail elderly on frailty, functional, and cognitive status: a systematic review
L Dedeyne, M Deschodt, S Verschueren… - … interventions in aging, 2017 - Taylor & Francis
Background Frailty is an aging syndrome caused by exceeding a threshold of decline across
multiple organ systems leading to a decreased resistance to stressors. Treatment for frailty …
multiple organ systems leading to a decreased resistance to stressors. Treatment for frailty …