[HTML][HTML] Carbohydrate-based drugs launched during 2000− 2021

X Cao, X Du, H Jiao, Q An, R Chen, P Fang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Carbohydrates are fundamental molecules involved in nearly all aspects of lives, such as
being involved in formating the genetic and energy materials, supporting the structure of …

[HTML][HTML] Challenges and strategies in anti-cancer nanomedicine development: An industry perspective

JI Hare, T Lammers, MB Ashford, S Puri, G Storm… - Advanced drug delivery …, 2017 - Elsevier
Successfully translating anti-cancer nanomedicines from pre-clinical proof of concept to
demonstration of therapeutic value in the clinic is challenging. Having made significant …

Design and challenges of radiopharmaceuticals

K Vermeulen, M Vandamme, G Bormans… - Seminars in nuclear …, 2019 - Elsevier
This review describes general concepts with regard to radiopharmaceuticals for diagnostic
or therapeutic applications that help to understand the specific challenges encountered …

A review of performance of near-infrared fluorescence imaging devices used in clinical studies

B Zhu, EM Sevick-Muraca - The British journal of radiology, 2015 - academic.oup.com
Near-infrared fluorescence (NIRF) molecular imaging holds great promise as a new “point-of-
care” medical imaging modality that can potentially provide the sensitivity of nuclear …

Recent advances in nuclear and hybrid detection modalities for image-guided surgery

MN Van Oosterom, DDD Rietbergen… - Expert review of …, 2019 - Taylor & Francis
Introduction: Radioguided surgery is an ever-evolving part of nuclear medicine. In fact, this
nuclear medicine sub-discipline actively bridges non-invasive molecular imaging with …

Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 111In-tilmanocept

Z Varasteh, F Hyafil, N Anizan, D Diallo, R Aid-Launais… - EJNMMI research, 2017 - Springer
Background Atherosclerotic plaque phenotypes are classified based on the extent of
macrophage infiltration into the lesions, and the presence of certain macrophage subsets …

99mTc-Tilmanocept: a novel molecular agent for lymphatic map** and sentinel lymph node localization

DS Surasi, J O'Malley… - Journal of nuclear …, 2015 - Soc Nuclear Med
Preoperative lymphatic map** in conjunction with intraoperative γ-probe detection is
widely used for sentinel node localization in melanoma, breast cancer, and other …

The basics of sentinel lymph node biopsy: anatomical and pathophysiological considerations and clinical aspects

NU Dogan, S Dogan, G Favero, C Köhler… - Journal of …, 2019 - Wiley Online Library
Sentinel lymph node (SLN) is the first node to receive the drainage directly from a tumor.
Detection and pathological examination of the SLN is an important oncological procedure …

Repurposing molecular imaging and sensing for cancer image–guided surgery

SB Mondal, CM O'Brien, K Bishop… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Gone are the days when medical imaging was used primarily to visualize anatomic
structures. The emergence of molecular imaging (MI), championed by radiolabeled 18F …

[HTML][HTML] Image-guided surgery using near-infrared Turn-ON fluorescent nanoprobes for precise detection of tumor margins

R Blau, Y Epshtein, E Pisarevsky, G Tiram… - Theranostics, 2018 - ncbi.nlm.nih.gov
Complete tumor removal during surgery has a great impact on patient survival. To that end,
the surgeon should detect the tumor, remove it and validate that there are no residual cancer …