Management of rheumatoid arthritis: an overview
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease of unknown etiology,
primarily affecting the joints, then extra-articular manifestations can occur. Due to its …
primarily affecting the joints, then extra-articular manifestations can occur. Due to its …
The pathogenesis of rheumatoid arthritis
IB McInnes, G Schett - New England Journal of Medicine, 2011 - Mass Medical Soc
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Genetics of rheumatoid arthritis
L Padyukov - Seminars in immunopathology, 2022 - Springer
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease involving symmetric joints
and is generally characterized by persistent pain, tenderness, and destruction of joints. The …
and is generally characterized by persistent pain, tenderness, and destruction of joints. The …
The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting
V Malmström, AI Catrina, L Klareskog - Nature Reviews Immunology, 2017 - nature.com
Patients with rheumatoid arthritis can be divided into two major subsets characterized by the
presence versus absence of antibodies to citrullinated protein antigens (ACPAs) and of …
presence versus absence of antibodies to citrullinated protein antigens (ACPAs) and of …
Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease
Some individuals with a particular disease-causing mutation or genotype fail to express
most if not all features of the disease in question, a phenomenon that is known as 'reduced …
most if not all features of the disease in question, a phenomenon that is known as 'reduced …
Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage
Autoimmune responses against posttranslationally modified antigens are a hallmark of
several autoimmune diseases. For example, antibodies against citrullinated protein antigens …
several autoimmune diseases. For example, antibodies against citrullinated protein antigens …
The role of autoantibodies in the pathophysiology of rheumatoid arthritis
V Derksen, TWJ Huizinga… - Seminars in …, 2017 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation.
The presence of autoantibodies in the sera of RA patients has provided many clues to the …
The presence of autoantibodies in the sera of RA patients has provided many clues to the …
Linkage of periodontitis and rheumatoid arthritis: current evidence and potential biological interactions
The association between rheumatoid arthritis (RA) and periodontal disease (PD) has been
the focus of numerous investigations driven by their common pathological features. RA is an …
the focus of numerous investigations driven by their common pathological features. RA is an …
Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis
Rheumatoid arthritis (RA) is now clearly a true autoimmune disease with accumulating
evidence of pathogenic disease‐specific autoimmunity to citrullinated proteins. Citrullination …
evidence of pathogenic disease‐specific autoimmunity to citrullinated proteins. Citrullination …
Host and bacterial factors linking periodontitis and rheumatoid arthritis
A Krutyhołowa, K Strzelec, A Dziedzic… - Frontiers in …, 2022 - frontiersin.org
Observations from numerous clinical, epidemiological and serological studies link
periodontitis with severity and progression of rheumatoid arthritis. The strong association is …
periodontitis with severity and progression of rheumatoid arthritis. The strong association is …