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Multiple sclerosis progression: time for a new mechanism-driven framework
Traditionally, multiple sclerosis has been categorised by distinct clinical descriptors—
relapsing-remitting, secondary progressive, and primary progressive—for patient care …
relapsing-remitting, secondary progressive, and primary progressive—for patient care …
Depressive symptoms, anxiety and cognitive impairment: emerging evidence in multiple sclerosis
Neuropsychiatric abnormalities may be broadly divided in two categories: disorders of
mood, affect, and behavior and abnormalities affecting cognition. Among these conditions …
mood, affect, and behavior and abnormalities affecting cognition. Among these conditions …
Modern network science of neurological disorders
Modern network science has revealed fundamental aspects of normal brain-network
organization, such as small-world and scale-free patterns, hierarchical modularity, hubs and …
organization, such as small-world and scale-free patterns, hierarchical modularity, hubs and …
Clinical and imaging assessment of cognitive dysfunction in multiple sclerosis
In patients with multiple sclerosis (MS), grey matter damage is widespread and might
underlie many of the clinical symptoms, especially cognitive impairment. This relation …
underlie many of the clinical symptoms, especially cognitive impairment. This relation …
Resting-state functional MR imaging: a new window to the brain
Resting-state (RS) functional magnetic resonance (MR) imaging constitutes a novel
paradigm that examines spontaneous brain function by using blood oxygen level …
paradigm that examines spontaneous brain function by using blood oxygen level …
The organization of physiological brain networks
One of the central questions in neuroscience is how communication in the brain is organized
under normal conditions and how this architecture breaks down in neurological disease. It …
under normal conditions and how this architecture breaks down in neurological disease. It …
Information processing speed in multiple sclerosis: Past, present, and future
Background: Information processing speed (IPS) is a prevalent cognitive impairment in
multiple sclerosis (MS). Objectives: This review aims to summarize the methods applied to …
multiple sclerosis (MS). Objectives: This review aims to summarize the methods applied to …
Network collapse and cognitive impairment in multiple sclerosis
The current field of multiple sclerosis (MS) research is an active and highly interesting one:
structural abnormalities such as inflammatory lesions and brain atrophy are studied with a …
structural abnormalities such as inflammatory lesions and brain atrophy are studied with a …
Potential biological contributers to the sex difference in multiple sclerosis progression
Multiple sclerosis (MS) is an immune-mediated disease that targets the myelin sheath of
central nervous system (CNS) neurons leading to axon injury, neuronal death, and …
central nervous system (CNS) neurons leading to axon injury, neuronal death, and …
Thalamus structure and function determine severity of cognitive impairment in multiple sclerosis
Objective: This study investigates whether changes in functional connectivity, diffusivity, and
volume of the thalamus can explain different severities of cognitive impairment in multiple …
volume of the thalamus can explain different severities of cognitive impairment in multiple …