Diabetes mellitus is one of the most common metabolic diseases in the developed world,
and is associated either with the impaired secretion of insulin or with the resistance of cells …

Pharmacological targeting of mitochondrial ion channels is emerging as a promising
approach to eliminate cancer cells; as most of these channels are differentially expressed …

Mitochondrial potassium channels have been described as important factors in cell pro-life
and death phenomena. The activation of mitochondrial potassium channels, such as ATP …

Significance: Mitochondria undergo constant morphological changes through fusion, fission,
and mitophagy. As the key organelle in cells, mitochondria are responsible for numerous …

The field of mitochondrial ion channels underwent a rapid development during the last
decade, thanks to the molecular identification of some of the nuclear-encoded organelle …

Mitochondria are key regulators of cell survival and are involved in a plethora of
mechanisms, such as metabolism, Ca2+ signaling, reactive oxygen species (ROS) …

Mitochondria are involved in multiple cellular tasks, such as ATP synthesis, metabolism,
metabolite and ion transport, regulation of apoptosis, inflammation, signaling, and …

Mitochondria are bioenergetic organelles with a plethora of fundamental functions ranging
from metabolism and ATP production to modulation of signaling events leading to cell …

In this paper, the current challenges of mitochondrial potassium channels research were
critically reviewed. Even though recent progress in understanding K+ traffic in mitochondria …

Non-small cell lung cancer (NSCLC) has a poor prognosis with a 5 year survival rate of
only~ 10%. Important driver mutations underlying NSCLC affect the epidermal growth factor …