[HTML][HTML] Magnetic nanoparticles for ferroptosis cancer therapy with diagnostic imaging

MJ Ko, S Min, H Hong, W Yoo, J Joo, YS Zhang… - Bioactive Materials, 2024 - Elsevier
Ferroptosis offers a novel method for overcoming therapeutic resistance of cancers to
conventional cancer treatment regimens. Its effective use as a cancer therapy requires a …

Harnessing the therapeutic potential of extracellular vesicles for biomedical applications using multifunctional magnetic nanomaterials

L Yang, KD Patel, C Rathnam, R Thangam, Y Hou… - Small, 2022 - Wiley Online Library
Extracellular vesicles (eg, exosomes) carrying various biomolecules (eg, proteins, lipids,
and nucleic acids) have rapidly emerged as promising platforms for many biomedical …

Nanoarchitectonics of in Situ Antibiotic-Releasing Acicular Nanozymes for Targeting and Inducing Cuproptosis-like Death to Eliminate Drug-Resistant Bacteria

Z Hu, J Shan, X **, W Sun, L Cheng, XL Chen… - ACS …, 2024 - ACS Publications
A series of progress has been made in the field of antimicrobial use of nanozymes due to
their superior stability and decreased susceptibility to drug resistance. However, catalytically …

Opsonized nanoparticles target and regulate macrophage polarization for osteoarthritis therapy: A trap** strategy

L Kou, H Huang, Y Tang, M Sun, Y Li, J Wu… - Journal of Controlled …, 2022 - Elsevier
Osteoarthritis (OA) is a chronic disease caused by joint inflammation. Its occurrence and
development depend on a continuous inflammation environment. The activated M1 …

Modulation of macrophages by in situ ligand bridging

SY Kim, R Thangam, N Kang, H Hong… - Advanced Functional …, 2023 - Wiley Online Library
Extracellular matrix (ECM) proteins containing cell‐attachable Arg‐Gly‐Asp (RGD)
sequences exhibit variable bridging and non‐bridging in fibronectin‐collagen and laminin …

A Novel Superparamagnetic Multifunctional Nerve Scaffold: A Remote Actuation Strategy to Boost In Situ Extracellular Vesicles Production for Enhanced Peripheral …

B **a, X Gao, J Qian, S Li, B Yu, Y Hao… - Advanced …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) have inherent advantages over cell‐based therapies in
regenerative medicine because of their cargos of abundant bioactive cues. Several …

Ligand coupling and decoupling modulates stem cell fate

R Thangam, SY Kim, N Kang, H Hong… - Advanced Functional …, 2023 - Wiley Online Library
In natural microenvironment, various proteins containing adhesive ligands in fibrous and
non‐fibrous structures dynamically couple and decouple to regulate stem cell fate. Herein …

Photonic control of image-guided ferroptosis cancer nanomedicine

MJ Ko, W Yoo, S Min, YS Zhang, J Joo, H Kang… - Coordination Chemistry …, 2024 - Elsevier
Photonic nanomaterials, characterized by their remarkable photonic tunability, empower a
diverse range of applications, including cutting-edge advances in cancer nanomedicine …

Transformative breakthrough in cancer phototheranostics utilizing bioinspired chemistry of polydopamine-based multifunctional nanostructures

KC Nanthini, R Thangam, L Karthikeyan… - Coordination Chemistry …, 2024 - Elsevier
Polydopamine (PDA), a biocompatible and biodegradable polymer derived from mussels,
exhibits highly advantageous properties for biomedical utilization such as strong adhesive …

Laser-activatable oxygen self-supplying nanoplatform for efficiently overcoming colorectal cancer resistance by enhanced ferroptosis and alleviated hypoxic …

H Jiang, H Tian, Z Wang, B Li, R Chen, K Luo… - Biomaterials …, 2023 - spj.science.org
Background Colorectal cancer (CRC) is the second most deadly cancer worldwide, with
chemo-resistance remaining a major obstacle in CRC treatment. Notably, the imbalance of …