Role of NRF2 in ovarian cancer

G Tossetta, S Fantone, E Montanari, D Marzioni… - Antioxidants, 2022 - mdpi.com
Among gynaecologic malignancies, ovarian cancer is one of the most dangerous, with a
high fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …

[HTML][HTML] LncRNA H19: A novel oncogene in multiple cancers

J Yang, M Qi, X Fei, X Wang, K Wang - International journal of …, 2021 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are a series of non-coding RNAs that lack open reading
frameworks. Accumulating evidence suggests important roles for lncRNAs in various …

Atorvastatin enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction via up-regulating long non-coding RNA …

P Huang, L Wang, Q Li, X Tian, J Xu, J Xu… - Cardiovascular …, 2020 - academic.oup.com
Aims Naturally secreted nanovesicles, known as exosomes, play important roles in stem cell-
mediated cardioprotection. We have previously demonstrated that atorvastatin (ATV) …

DNA methylation dynamics of the human preimplantation embryo

ZD Smith, MM Chan, KC Humm, R Karnik… - Nature, 2014 - nature.com
In mammals, cytosine methylation is predominantly restricted to CpG dinucleotides and
stably distributed across the genome, with local, cell-type-specific regulation directed by …

[HTML][HTML] X-inactivation, imprinting, and long noncoding RNAs in health and disease

JT Lee, MS Bartolomei - Cell, 2013 - cell.com
X chromosome inactivation and genomic imprinting are classic epigenetic processes that
cause disease when not appropriately regulated in mammals. Whereas X chromosome …

Evolution and functions of long noncoding RNAs

CP Ponting, PL Oliver, W Reik - Cell, 2009 - cell.com
RNA is not only a messenger operating between DNA and protein. Transcription of
essentially the entire eukaryotic genome generates a myriad of non-protein-coding RNA …

Genomic imprinting: the emergence of an epigenetic paradigm

AC Ferguson-Smith - Nature Reviews Genetics, 2011 - nature.com
The emerging awareness of the contribution of epigenetic processes to genome function in
health and disease is underpinned by decades of research in model systems. In particular …

Beyond DNA: integrating inclusive inheritance into an extended theory of evolution

É Danchin, A Charmantier, FA Champagne… - Nature reviews …, 2011 - nature.com
Many biologists are calling for an'extended evolutionary synthesis' that would'modernize the
modern synthesis' of evolution. Biological information is typically considered as being …

The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

A Keniry, D Oxley, P Monnier, M Kyba, L Dandolo… - Nature cell …, 2012 - nature.com
The H19 large intergenic non-coding RNA (lincRNA) is one of the most highly abundant and
conserved transcripts in mammalian development, being expressed in both embryonic and …

[HTML][HTML] Regulation of lncRNA and its role in cancer metastasis

J Li, H Meng, Y Bai, K Wang - Oncology research, 2016 - ncbi.nlm.nih.gov
Metastasis is the primary cause of cancer-related death all over the world. Metastasis is a
process by which cancer spreads from the place at which it first arose to distant locations in …